Poly (adenosine diphosphate [ADP]–ribose) polymerases inhibitors (PARPi), the first
clinically approved drug that exhibits synthetic lethality, are moving to the forefront of cancer …

Bisdemethoxycurcumin (BDMC) is the main active ingredient that is isolated from
Zingiberaceae plants, wherein it has excellent anti-tumor effects. However, insolubility in …

In this study, a series of glutathione-responsive (GSH-responsive) amphiphilic comb
polymers LPGE-SS-n were synthesized based on linear polyglycidol (LPG). The …

Glioma, in which a malignant tumor cell occurs in neural mesenchymal cells, has a rapid
progression and poor prognosis, which is still far from desirable in clinical treatments. We …

The purpose of the present work was to encapsulate zingerone (a bioactive compound from
ginger) by self-assembling peptides derived from fish viscera. The encapsulation conditions …

Linear polyglycidol (LPG) has emerged as a polyethylene glycol (PEG) alternative in novel
surfactant development due to its unique advantages, such as high bioavailability and …

In this regard, we developed vitexin (Vi)-loaded D-ɑ-tocopherol polyethylene glycol
succinate, polyvinylpyrrolidone K30 and sodium cholate mixed micelles (Vi-MMs) mainly for …

Due to low aqueous solubility and poor bioavailability of the flavone baicalein (BIC), a nano-
micelle of delivery system was developed. Preparation of BIC-loaded crown ether-mPEG …

Background. Nanotargeted preparations can enhance the safety and effectiveness of
medication by altering the pharmacokinetic behavior of drugs in the human body, and …

From ancient days to present days, the delivery of drugs via gastrointestinal tract is the
utmost preferred route. The oral delivery of drugs possesses advantages such as ease of …