Physical exercise is of great significance for maintaining human health. Exercise can
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …

There have been hundreds of millions of cases of coronavirus disease 2019 (COVID-19),
which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With …

Resilience to Alzheimer's disease is an uncommon combination of high disease burden
without dementia that offers valuable insights into limiting clinical impact. Here we assessed …

There is a dire need for due innovative therapeutic modalities to improve outcomes of AD
patients. In this study, we tested whether cannabidiol (CBD) improves outcomes in a …

Nuclear factor (erythroid-derived 2)-like 2 (NRF2) is a redox-sensitive transcription factor that
binds to the antioxidant response element consensus sequence, decreasing reactive …

Synaptic molecular characterization is limited for Alzheimer's disease (AD). Our newly
invented mass cytometry–based method, synaptometry by time of flight (SynTOF), was used …

Based on accumulating evidence, vascular factors contribute to cognitive decline and
dementia. Mitochondrial dysfunction is the core pathophysiological mechanism …

Background Previous studies on the relationship between cognitive impairment and adverse
outcomes among geriatric inpatients are not representative of older inpatients in China …

Background We have proposed that cognitive resilience (CR) counteracts brain damage
from Alzheimer's disease (AD) or AD-related dementias such that older individuals who …

Background Cognitive impairment is a major health concern in older adults. Few studies
have examined the association between environmental factors and cognitive impairment …