The transcription factor NF-κB regulates multiple aspects of innate and adaptive immune
functions and serves as a pivotal mediator of inflammatory response. In the first part of this …

Microbe–host communication is essential to maintain vital functions of a healthy host, and its
disruption has been associated with several diseases, including Crohn's disease and …

A transcriptional regulatory nuclear factor kappa B (NF-ΚB) protein is a modulator of cellular
biological activity via binding to a promoter region in the nucleus and transcribing various …

This systematic review was designed to determine the clinical efficacy and safety of
curcumin supplementation for pediatric patients based on clinical trials in children. We …

Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and
remission of the disease. The etiology of IBD is not fully understood. Many studies point to …

Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disease that can
involve any part of the gastrointestinal tract. It includes two main disorders: Crohn's disease …

Alzheimer disease (AD) is the first progressive neurodegenerative disease worldwide, and
the disease is characterized by an accumulation of amyloid in the brain and …

Cell death is an essential immunological apparatus of host defense, but dysregulation of
mutually inclusive cell deaths poses severe threats during microbial and parasitic infections …

Fibrosis is considered a complex form of tissue damage commonly present in the end stage
of many diseases. It is also related to a high percentage of death, whose predominant …

Recent genetic studies on Alzheimer's disease (AD) have brought microglia under the
spotlight, as loci associated with AD risk are enriched in genes expressed in microglia …