Genome-wide association studies (GWAS) involve testing genetic variants across the
genomes of many individuals to identify genotype–phenotype associations. GWAS have …

Schizophrenia is a severe neuropsychiatric disorder with a longstanding history of
neurobiological investigation. Although the underlying causal mechanisms remain …

Fitness landscapes, depict how genotypes manifest at the phenotypic level and form the
basis of our understanding of many areas of biology,,,,,, yet their properties remain elusive …

Background Despite evidence from twin and family studies for an important contribution of
genetic factors to both childhood and adult onset psychiatric disorders, identifying robustly …

Epistasis occurs when the effect of a mutation depends on its carrier's genetic background.
Despite increasing evidence that epistasis for fitness is common, its role during evolution is …

Selection for inflorescence architecture with improved flower production and yield is
common to many domesticated crops. However, tomato inflorescences resemble wild …

The Drosophila melanogaster Genetic Reference Panel (DGRP) is a community resource of
205 sequenced inbred lines, derived to improve our understanding of the effects of naturally …

Genome-wide association studies (GWASs) have become the focus of the statistical analysis
of complex traits in humans, successfully shedding light on several aspects of genetic …

There is abundant variation in gene expression between individuals, populations, and
species. The evolution of gene regulation and expression within and between species is …

With the advent of rapid genotyping and next‐generation sequencing technologies, genome‐
wide association study (GWAS) has become a routine strategy for decoding genotype …