Parasite lipids can serve as signaling molecules, importantmembrane components, energy
suppliers, and pathogenesis factors critical for survival. Functional roles of lipid changes in …

The increase in atmospheric oxygen levels imposed significant environmental pressure on
primitive organisms concerning intracellular oxygen concentration management. Evidence …

The current framework of evolutionary theory postulates that evolution relies on random
mutations generating a diversity of phenotypes on which natural selection acts. This …

Abstract Cytochrome P450 enzymes (P450) play essential roles in redox metabolism in all
domains of life including detoxification reactions and sterol biosynthesis. The activity of …

Inter‐tissue communication is instrumental to coordinating the whole‐body level behaviour
for complex multicellular organisms. However, little is known about the regulation of inter …

Background Leishmania donovani, a protozoan parasite, is the primary causative agent for
visceral leishmaniasis. Toxicity and increased resistance to existing drugs have led to an …

Lipids are essential components of all living cells. In an oenological context, the supply of
unsaturated lipids in grape juice allows the yeasts to grow and ferment, despite very low …

Cholesterol synthesis is a highly oxygen-dependent process. Paradoxically, hypoxia is
correlated with an increase in cellular and systemic cholesterol levels and risk of …

Background Leishmania donovani is a protozoan parasite, a primary causative agent of
visceral leishmaniasis. Sterol produced via the mevalonate pathway, show differences in …

Lipidomics is the study of the lipid molecules that are found in animal, plant, and bacterial
cells. Recent research in this field has been driven by the development of sensitive new …