Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an
immunoglobulin E (IgE)-mediated inflammation of the membranes lining the nose (1). It was …

We will review the epidemiology, risk factors, and consequences of obstructive sleep apnea
(OSA) and short/long sleep duration. Obstructive sleep apnea is a disease characterized by …

BACKGROUND: Allergic rhinitis represents a global health problem affecting 10% to 20% of
the population. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines have been …

Objective To undertake a multicentre epidemiological study reflecting acromegaly in Spain.
Design Voluntary reporting of data on patients with acromegaly to an online database, by …

Obstructive sleep apnea (OSA) syndrome is a disorder characterized by repetitive episodes
of upper airway obstruction that occur during sleep. Associated features include loud …

Acromegaly and gigantism are due to excess GH production, usually as a result of a pituitary
adenoma. The incidence of acromegaly is 5 cases per million per year and the prevalence is …

Although acromegaly is a rare disease, the clinical, economic and health-related quality of
life (HRQoL) burden is considerable due to the broad spectrum of comorbidities as well as …

It is increasingly recognized that disruption of sleep and reduced amounts of sleep can have
significant adverse cardiovascular consequences. For example, obstructive sleep apnea …

Pituitary adenomas often present with the symptoms of hormonal hypersecretion, and
although medical therapy is available for most hyperfunctioning states, it is not curative. As a …

Context: Persistently elevated GH and IGF-I levels are associated with increased mortality.
Their response to somatostatin analogs (SSA) is variable. Objective: The objective of this …