Still a “hidden island”? The rodent insular cortex in drug seeking, reward, and risk

MS McGregor, RT LaLumiere - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Abstract MCGREGOR, MS, and RT LaLumiere. Still a “hidden island”? The rodent insular
cortex in drug seeking, reward, and risk. NEUROSCI BIOBEHAV REV 21 (1) XXX-XXX …

From compulsivity to compulsion: the neural basis of compulsive disorders

TW Robbins, P Banca, D Belin - Nature Reviews Neuroscience, 2024 - nature.com
Compulsive behaviour, an apparently irrational perseveration in often maladaptive acts, is a
potential transdiagnostic symptom of several neuropsychiatric disorders, including …

[HTML][HTML] Connecting circuits with networks in addiction neuroscience: A salience network perspective

AK Cushnie, W Tang, SR Heilbronner - International journal of molecular …, 2023 - mdpi.com
Human neuroimaging has demonstrated the existence of large-scale functional networks in
the cerebral cortex consisting of topographically distant brain regions with functionally …

[HTML][HTML] Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype

A Passeri, D Municchi, G Cavalieri… - Frontiers in Behavioral …, 2023 - frontiersin.org
Despite a lack of agreement on its definition and inclusion as a specific diagnosable
disturbance, the food addiction construct is supported by several neurobiological and …

[HTML][HTML] High frequency deep brain stimulation of the dorsal raphe nucleus prevents methamphetamine priming-induced reinstatement of drug seeking in rats

L Zhang, S Meng, E Huang, T Di, Z Ding… - Translational …, 2024 - nature.com
Drug addiction represents a multifaceted and recurrent brain disorder that possesses the
capability to create persistent and ineradicable pathological memory. Deep brain stimulation …

[HTML][HTML] Emotion in action: when emotions meet motor circuits

A Braine, F Georges - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
The brain is a remarkably complex organ responsible for a wide range of functions,
including the modulation of emotional states and movement. Neuronal circuits are believed …

[HTML][HTML] Early-onset smoking theory of compulsivity development: a neurocognitive model for the development of compulsive tobacco smoking

AA Conti, AM Baldacchino - Frontiers in Psychiatry, 2023 - frontiersin.org
According to the literature, individuals who start tobacco smoking during adolescence are at
greater risk of developing severe tobacco addiction and heavier smoking behavior in …

A disinhibitory microcircuit of the orbitofrontal cortex mediates cocaine preference in mice

Z Huang, X Wei, J Tian, Y Fu, J Dong, Y Wang… - Molecular …, 2024 - nature.com
Both clinical and animal studies showed that the impaired functions of the orbitofrontal
cortex (OFC) underlie the compulsive drug-seeking behavior of drug addiction. However, the …

The gut microbiome modulates the susceptibility to traumatic stress in a sex‐dependent manner

D Shen, L Chang, F Su, S Huang, H Xu… - Journal of …, 2024 - Wiley Online Library
Post‐traumatic stress disorder (PTSD), a psychological condition triggered by exposure to
extreme or chronic stressful events, exhibits a sex bias in incidence and clinical …

The secondary visual cortex mediated the enhancement of associative learning on methamphetamine self-administration behaviors

C Wang, D Cao, N Wu, Y Zhu, J Li - Psychopharmacology, 2024 - Springer
Rationale Methamphetamine addiction is a persistent and intractable pathological learning
and memory, whereas no approved therapeutics is available. However, few attentions have …