Autoimmune encephalitis defines brain inflammation caused by a misdirected immune
response against self-antigens expressed in the central nervous system. It comprises a …

Paraneoplastic neurological syndromes (PNS) are the immune-mediated effects of a remote
cancer and are characterised by an autoantibody response against antigens expressed by …

Autoantibodies against the extracellular domain of the N-methyl-d-aspartate receptor
(NMDAR) NR1 subunit cause a severe and common form of encephalitis. To better …

A rapidly expanding and clinically distinct group of CNS diseases are caused by pathogenic
autoantibodies that target neuroglial surface proteins. Despite immunotherapy, patients with …

Paraneoplastic neurological syndromes (PNSs) are rare complications of systemic cancers
that can affect all parts of the central and/or peripheral nervous system. A body of …

The field of autoimmune neurology is rapidly evolving, and recent discoveries have
advanced our understanding of disease aetiologies. In this article, we review the key …

Febrile infection‐related epilepsy syndrome (FIRES) is a rare catastrophic epileptic
encephalopathy that presents suddenly in otherwise normal children and young adults …

Autoantibodies are a hallmark of numerous neurological disorders, including multiple
sclerosis, autoimmune encephalitides and neuromyelitis optica. Whilst well understood in …

Autoimmune neuroinflammatory diseases are a group of disorders resulting from abnormal
immune responses in the nervous system, causing inflammation and tissue damage. The …

Epilepsy is a common chronic neurological disorder in modern society. One of the major
unmet challenges is that current antiseizure medications are basically not disease …