RNA-seq analysis of extradomain A and extradomain B fibronectin as extracellular matrix markers for cancer

RC Hall, AM Vaidya, WP Schiemann, Q Pan, ZR Lu - Cells, 2023 - mdpi.com
Alternatively spliced forms of fibronectin, called oncofetal fibronectin, are aberrantly
expressed in cancer, with little to no expression in normal tissue, making them attractive …

Extracellular targets to reduce excessive scarring in response to tissue injury

J Fertala, ML Wang, M Rivlin, PK Beredjiklian… - Biomolecules, 2023 - mdpi.com
Excessive scar formation is a hallmark of localized and systemic fibrotic disorders. Despite
extensive studies to define valid anti-fibrotic targets and develop effective therapeutics …

[HTML][HTML] Regulation of cell locomotion by nanosecond-laser-induced hydroxyapatite patterning

SH Um, J Lee, IS Song, MR Ok, YC Kim, HS Han… - Bioactive Materials, 2021 - Elsevier
Hydroxyapatite, an essential mineral in human bones composed mainly of calcium and
phosphorus, is widely used to coat bone graft and implant surfaces for enhanced …

Sacrificial biomaterials in 3D fabrication of scaffolds for tissue engineering applications

C Wang, Y Zhou - … of Biomedical Materials Research Part B …, 2024 - Wiley Online Library
Abstract Three‐dimensional (3D) printing technology has progressed exceedingly in the
area of tissue engineering. Despite the tremendous potential of 3D printing, building …

Functionalization of zirconia ceramic with fibronectin proteins enhanced bioactivity and osteogenic response of osteoblast-like cells

LM Aung, JCY Lin, E Salamanca, YF Wu… - … in Bioengineering and …, 2023 - frontiersin.org
Introduction: To overcome the genuine bioinert properties of zirconia ceramic,
functionalization of the surface with the bioactive protein fibronectin was conducted …

Targeting Wnt/β-catenin signaling and its interplay with TGF-β and Notch signaling pathways for the treatment of chronic wounds

DB Gumede, H Abrahamse, NN Houreld - Cell Communication and …, 2024 - Springer
Wound healing is a tightly regulated process that ensures tissue repair and normal function
following injury. It is modulated by activation of pathways such as the transforming growth …

Proteomic analysis of bone marrow-derived mesenchymal stem cell extracellular vesicles from healthy donors: implications for proliferation, angiogenesis, Wnt …

JD McBride, L Rodriguez-Menocal, W Guzman… - Stem cell research & …, 2021 - Springer
Background Bone marrow-derived mesenchymal stem cells (BM-MSCs) have shown
therapeutic potential in various in vitro and in vivo studies in cutaneous wound healing …

Targeting collagen in tumor extracellular matrix as a novel targeted strategy in cancer immunotherapy

J Liu, D Pan, X Huang, S Wang, H Chen, YZ Zhu… - Frontiers in …, 2023 - frontiersin.org
Collagen, the most abundant protein in mammal, is widely expressed in tissues and organs,
as well as tumor extracellular matrix. Tumor collagen mainly accumulates in tumor stroma or …

FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells

N Liu, D Li, D Liu, Y Liu, J Lei - Journal of Translational Internal …, 2023 - degruyter.com
Background Fos-related antigen 2 (FOSL2) plays a facilitative role in fibrotic disease;
however, its role in renal fibrosis remains unclear. This study aimed to clarify the role and …

Animal model of subretinal fibrosis without active choroidal neovascularization

S Zandi, Y Li, L Jahnke, A Schweri-Olac… - Experimental eye …, 2023 - Elsevier
Subretinal fibrosis can occur during neovascular age-related macular degeneration (nAMD)
and consequently provokes progressing deterioration of AMD patient's vision. Intravitreal …