RNA-seq analysis of extradomain A and extradomain B fibronectin as extracellular matrix markers for cancer
Alternatively spliced forms of fibronectin, called oncofetal fibronectin, are aberrantly
expressed in cancer, with little to no expression in normal tissue, making them attractive …
expressed in cancer, with little to no expression in normal tissue, making them attractive …
Extracellular targets to reduce excessive scarring in response to tissue injury
J Fertala, ML Wang, M Rivlin, PK Beredjiklian… - Biomolecules, 2023 - mdpi.com
Excessive scar formation is a hallmark of localized and systemic fibrotic disorders. Despite
extensive studies to define valid anti-fibrotic targets and develop effective therapeutics …
extensive studies to define valid anti-fibrotic targets and develop effective therapeutics …
[HTML][HTML] Regulation of cell locomotion by nanosecond-laser-induced hydroxyapatite patterning
Hydroxyapatite, an essential mineral in human bones composed mainly of calcium and
phosphorus, is widely used to coat bone graft and implant surfaces for enhanced …
phosphorus, is widely used to coat bone graft and implant surfaces for enhanced …
Sacrificial biomaterials in 3D fabrication of scaffolds for tissue engineering applications
Abstract Three‐dimensional (3D) printing technology has progressed exceedingly in the
area of tissue engineering. Despite the tremendous potential of 3D printing, building …
area of tissue engineering. Despite the tremendous potential of 3D printing, building …
Functionalization of zirconia ceramic with fibronectin proteins enhanced bioactivity and osteogenic response of osteoblast-like cells
Introduction: To overcome the genuine bioinert properties of zirconia ceramic,
functionalization of the surface with the bioactive protein fibronectin was conducted …
functionalization of the surface with the bioactive protein fibronectin was conducted …
Targeting Wnt/β-catenin signaling and its interplay with TGF-β and Notch signaling pathways for the treatment of chronic wounds
Wound healing is a tightly regulated process that ensures tissue repair and normal function
following injury. It is modulated by activation of pathways such as the transforming growth …
following injury. It is modulated by activation of pathways such as the transforming growth …
Proteomic analysis of bone marrow-derived mesenchymal stem cell extracellular vesicles from healthy donors: implications for proliferation, angiogenesis, Wnt …
JD McBride, L Rodriguez-Menocal, W Guzman… - Stem cell research & …, 2021 - Springer
Background Bone marrow-derived mesenchymal stem cells (BM-MSCs) have shown
therapeutic potential in various in vitro and in vivo studies in cutaneous wound healing …
therapeutic potential in various in vitro and in vivo studies in cutaneous wound healing …
Targeting collagen in tumor extracellular matrix as a novel targeted strategy in cancer immunotherapy
J Liu, D Pan, X Huang, S Wang, H Chen, YZ Zhu… - Frontiers in …, 2023 - frontiersin.org
Collagen, the most abundant protein in mammal, is widely expressed in tissues and organs,
as well as tumor extracellular matrix. Tumor collagen mainly accumulates in tumor stroma or …
as well as tumor extracellular matrix. Tumor collagen mainly accumulates in tumor stroma or …
FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells
N Liu, D Li, D Liu, Y Liu, J Lei - Journal of Translational Internal …, 2023 - degruyter.com
Background Fos-related antigen 2 (FOSL2) plays a facilitative role in fibrotic disease;
however, its role in renal fibrosis remains unclear. This study aimed to clarify the role and …
however, its role in renal fibrosis remains unclear. This study aimed to clarify the role and …
Animal model of subretinal fibrosis without active choroidal neovascularization
S Zandi, Y Li, L Jahnke, A Schweri-Olac… - Experimental eye …, 2023 - Elsevier
Subretinal fibrosis can occur during neovascular age-related macular degeneration (nAMD)
and consequently provokes progressing deterioration of AMD patient's vision. Intravitreal …
and consequently provokes progressing deterioration of AMD patient's vision. Intravitreal …