Matrisomal components involved in regenerative wound healing in axolotl and Acomys: implications for biomaterial development

N Avila-Martinez, M Gansevoort, J Verbakel… - Biomaterials …, 2023 - pubs.rsc.org
Achieving regeneration in humans has been a long-standing goal of many researchers.
Whereas amphibians like the axolotl (Ambystoma mexicanum) are capable of regenerating …

Method for high‐plex analysis of immune cells in human skin using the GeoMx system

B Ignatov, D Sortebech, T Emmanuel… - Scandinavian …, 2024 - Wiley Online Library
Specific T cell populations in the skin have been demonstrated as important disease drivers
in several dermatoses. Due to the unique skin architecture, these cells are not grouped …

UCHL1, besides leptin and fibronectin, also could be a sensitive marker of the relapsing–remitting type of multiple sclerosis

E Górska, M Tylicka, A Hermanowicz, E Matuszczak… - Scientific reports, 2023 - nature.com
Research on the markers of immunoregulatory response in multiple sclerosis (MS) is still of
great importance. The aim of our study was the evaluation of leptin, fibronectin, and UCHL1 …

Self‐healing supramolecular hydrogels with antibacterial abilities for wound healing

Z Hong, L Wu, Z Zhang, J Zhang, H Ren… - Journal of …, 2023 - Wiley Online Library
Wound healing due to skin defects is a growing clinical concern. Especially when infection
occurs, it not only leads to impair healing of the wound but even leads to the occurrence of …

Invasion-Associated Reorganization of Laminin 332 in Oral Squamous Cell Carcinomas: The Role of the Laminin γ2 Chain in Tumor Biology, Diagnosis, and Therapy

A Berndt, N Gaßler, M Franz - Cancers, 2022 - mdpi.com
Simple Summary The destructive growth of carcinomas is associated with crossing the
border between the epithelial and the connective tissue parts of an organ. One component …

[HTML][HTML] Temporal profiling and validation of oxidative stress-related genes in spinal cord injury

G Liu, B Deng, L Huo, S Jiang, X Fan, Y Mo, J Ren… - Brain research …, 2023 - Elsevier
Oxidative stress (OS) plays a pivotal role in the pathogenesis of spinal cord injury (SCI), yet
its underlying mechanisms remain elusive. In this study, we explored the OS phenotype in a …

Mechanotransduction through adhesion molecules: Emerging roles in regulating the stem cell niche

R Lim, A Banerjee, R Biswas, AN Chari… - Frontiers in Cell and …, 2022 - frontiersin.org
Stem cells have been shown to play an important role in regenerative medicine due to their
proliferative and differentiation potential. The challenge, however, lies in regulating and …

Enriched Graphene Oxide-Polypropylene Suture Threads Buttons Modulate the Inflammatory Pathway Induced by Escherichia coli Lipopolysaccharide

L Fonticoli, F Diomede, A Nanci, A Fontana… - International Journal of …, 2023 - mdpi.com
Graphene oxide (GO), derived from graphene, has remarkable chemical–physical properties
such as stability, strength, and thermal or electric conductivity and additionally shows …

[HTML][HTML] Matrikines in the skin: Origin, effects, and therapeutic potential

JP Sirois, A Heinz - Pharmacology & Therapeutics, 2024 - Elsevier
The extracellular matrix (ECM) represents a complex multi-component environment that has
a decisive influence on the biomechanical properties of tissues and organs. Depending on …

Essential elements for spatiotemporal delivery of growth factors within bio-scaffolds: A comprehensive strategy for enhanced tissue regeneration

T Chen, Y Jiang, JP Huang, J Wang, ZK Wang… - Journal of Controlled …, 2024 - Elsevier
The precise delivery of growth factors (GFs) in regenerative medicine is crucial for effective
tissue regeneration and wound repair. However, challenges in achieving controlled release …