Despite the recent advances in chemotherapeutic treatments against cancer, some types of
highly aggressive and invasive cancer develop drug resistance against conventional …

Epigenetic alterations such as DNA methylation, histone acetylation, and chromatin
remodeling can control gene expression by regulating gene transcription. DNA methylation …

Hypermethylation of transcription factor activating enhancer‑binding protein 2e (TFAP2E)
has been reported to be associated with chemoresistance to 5‑fluorouracil (5‑FU) in gastric …

Activating enhancer-binding protein 2 (AP-2) is a family of transcription factors (TFs) that
play crucial roles in regulating embryonic and oncogenic development. In addition to splice …

Hypermethylation of the transcription factor AP-2 epsilon (TFAP2E) gene affects 5-
fluorouridine (5-FU) resistance in gastric cancer (GC) patients. The epigenetic inhibitor 5 …

TFAP2E is a member of the activator protein-2 transcription factor family and acts as a tumor
suppressor in several types of cancer. Downregulation of TFAP2E expression is significantly …

Neuroblastoma is a childhood malignancy originating from the sympathetic nervous system
and accounts for approximately 15% of all pediatric cancer-related deaths. To newly identify …

2016-12-20 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

The AP-2 family of transcription factors consist of DNA-binding proteins: AP-2α to AP-2ε.
Members and homologs of this family are also known in frogs, fish and invertebrates. These …

The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the …