What is the impact of human umbilical cord mesenchymal stem cell transplantation on clinical treatment?

Q Xie, R Liu, J Jiang, J Peng, C Yang, W Zhang… - Stem cell research & …, 2020 - Springer
Background Human umbilical cord mesenchymal stem cells (HUC-MSCs) present in the
umbilical cord tissue are self-renewing and multipotent. They can renew themselves …

Behavioral assessment of sensory, motor, emotion, and cognition in rodent models of intracerebral hemorrhage

X Shi, H Bai, J Wang, J Wang, L Huang, M He… - Frontiers in …, 2021 - frontiersin.org
Intracerebral hemorrhage (ICH) is the second most common type of stroke and has one of
the highest fatality rates of any disease. There are many clinical signs and symptoms after …

Extracellular vesicles in physiology, pathology, and therapy of the immune and central nervous system, with focus on extracellular vesicles derived from mesenchymal …

S Koniusz, A Andrzejewska, M Muraca… - Frontiers in cellular …, 2016 - frontiersin.org
Extracellular vesicles (EVs) are membrane-surrounded structures released by most cell
types. They are characterized by a specific set of proteins, lipids and nucleic acids. EVs have …

Stem cell therapy: a promising therapeutic method for intracerebral hemorrhage

L Gao, W Xu, T Li, J Chen, A Shao, F Yan… - Cell …, 2018 - journals.sagepub.com
Spontaneous intracerebral hemorrhage (ICH) is one type of the most devastating
cerebrovascular diseases worldwide, which causes high morbidity and mortality. However …

Application of stem cells in stroke: a multifactorial approach

M Singh, PK Pandey, A Bhasin, MV Padma… - Frontiers in …, 2020 - frontiersin.org
Stroke has a debilitating effect on the human body and a serious negative effect on society,
with a global incidence of one in every six people. According to the World Health …

Peroxiredoxin 1-mediated activation of TLR4/NF-κB pathway contributes to neuroinflammatory injury in intracerebral hemorrhage

DL Liu, LX Zhao, S Zhang, JR Du - International Immunopharmacology, 2016 - Elsevier
The proinflammatory properties of extracellular peroxiredoxins (Prxs) via induction of Toll-
like receptor 4 (TLR4) activation have been gradually revealed under diverse stress …

[HTML][HTML] Mesenchymal stem cell application and its therapeutic mechanisms in intracerebral hemorrhage

G Yang, X Fan, M Mazhar, S Yang, H Xu… - Frontiers in cellular …, 2022 - frontiersin.org
Intracerebral hemorrhage (ICH) is one of the leading causes of death and long-term
disability worldwide. The ICH is characterized by motor and sensory dysfunction that is …

Mesenchymal stem cells for hemorrhagic stroke: status of preclinical and clinical research

MT Turnbull, AC Zubair, JF Meschia… - NPJ Regenerative …, 2019 - nature.com
Significant progress has been made during the past few decades in stem cell therapy
research for various diseases and injury states; however this has not been overwhelmingly …

Revolutionizing stroke recovery: unveiling the promise of stem cell therapy

LD Panos, P Bargiotas, M Arnold… - Drug design …, 2024 - Taylor & Francis
Stem cells, renowned for their unique regenerative capabilities, present significant hope in
treating stroke, a major cause of disability globally. This review offers a detailed analysis of …

[HTML][HTML] The role of stem cells in the therapy of stroke

M Ejma, N Madetko, A Brzecka, P Alster… - Current …, 2022 - ncbi.nlm.nih.gov
Background: Stroke is a major challenge in neurology due to its multifactorial genesis and
irreversible consequences. Processes of endogenous post-stroke neurogenesis, although …