[HTML][HTML] The role of inflammation, hypoxia, and opioid receptor expression in pain modulation in patients suffering from obstructive sleep apnea

P Kaczmarski, FF Karuga, B Szmyd, M Sochal… - International Journal of …, 2022 - mdpi.com
Obstructive sleep apnea (OSA) is a relatively common disease in the general population.
Besides its interaction with many comorbidities, it can also interact with potentially painful …

[HTML][HTML] Circadian rhythm disruption as a contributor to racial disparities in prostate cancer

SS Dasari, M Archer, NE Mohamed, AK Tewari… - Cancers, 2022 - mdpi.com
Simple Summary African American (AA) men have 2.4 times higher mortality rate due to
prostate cancer than White men in the United States. Evidence implicates circadian rhythm …

[HTML][HTML] BDNF and proBDNF serum protein levels in obstructive sleep apnea patients and their involvement in insomnia and depression symptoms

A Gabryelska, S Turkiewicz, M Ditmer… - Journal of Clinical …, 2022 - mdpi.com
Introduction: Obstructive sleep apnea (OSA) is a disorder that, apart from somatic sequelae,
increases the risk of developing psychiatric conditions. Brain-derived neurotrophic factor …

[HTML][HTML] Circadian clock disruptions link oxidative stress and systemic inflammation to metabolic syndrome in obstructive sleep apnea patients

X Li, X Liu, Q Meng, X Wu, X Bing, N Guo… - Frontiers in …, 2022 - frontiersin.org
Objectives: Obstructive sleep apnea (OSA) is an independent risk factor for metabolic
syndrome (MetS). Recent studies have indicated that circadian clock genes were …

[HTML][HTML] REM-OSA as a Tool to Understand Both the Architecture of Sleep and Pathogenesis of Sleep Apnea—Literature Review

FF Karuga, P Kaczmarski, P Białasiewicz… - Journal of Clinical …, 2023 - mdpi.com
Sleep is a complex physiological state, which can be divided into the non-rapid eye
movement (NREM) phase and the REM phase. Both have some unique features and …

Is obstructive sleep apnea a circadian rhythm disorder?

J Šmon, E Kočar, T Pintar… - Journal of sleep …, 2023 - Wiley Online Library
Obstructive sleep apnea is the most common sleep‐related breathing disorder worldwide
and remains underdiagnosed. Its multiple associated comorbidities contribute to a …

[HTML][HTML] Hypoxia induces alterations in the circadian rhythm in patients with chronic respiratory diseases

M Castillejos-López, Y Romero, A Varela-Ordoñez… - Cells, 2023 - mdpi.com
The function of the circadian cycle is to determine the natural 24 h biological rhythm, which
includes physiological, metabolic, and hormonal changes that occur daily in the body. This …

[HTML][HTML] Obstructive sleep apnea, circadian clock disruption, and metabolic consequences

M Malicki, FF Karuga, B Szmyd, M Sochal… - Metabolites, 2022 - mdpi.com
Obstructive sleep apnea (OSA) is a chronic disorder characterized by recurrent episodes of
apnea and hypopnea during sleep. It is associated with various cardiovascular and …

Associations between sleep-related symptoms, obesity, cardiometabolic conditions, brain structural alterations and cognition in the UK biobank

J Yu, F Morys, A Dagher, A Lajoie, T Gomes, EY Ock… - Sleep Medicine, 2023 - Elsevier
Objectives Sleep disturbances are increasingly recognized as adversely affecting brain
health in aging. Our aim was to investigate interrelations between subjective sleep-related …

[HTML][HTML] Chronic intermittent hypoxia accelerates cardiac dysfunction and cardiac remodeling during cardiac pressure overload in mice and can be alleviated by PHD3 …

X Xu, PH Zhen, FC Yu, T Wang, SN Li, Q Wei… - Frontiers in …, 2022 - frontiersin.org
Obstructive sleep apnea (OSA) accelerates the progression of chronic heart failure (CHF).
OSA is characterized by chronic intermittent hypoxia (CIH), and CIH exposure accelerates …