[HTML][HTML] How vascular smooth muscle cell phenotype switching contributes to vascular disease

G Cao, X Xuan, J Hu, R Zhang, H Jin… - Cell Communication and …, 2022 - Springer
Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …

[HTML][HTML] Immune and inflammatory mechanisms of abdominal aortic aneurysm

AC Marquez-Sanchez, EK Koltsova - Frontiers in immunology, 2022 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-
mediated infiltration and a destruction of the aortic wall during AAA development plays …

[HTML][HTML] Curcumin and cardiovascular diseases: Focus on cellular targets and cascades

AM Pourbagher-Shahri, T Farkhondeh… - Biomedicine & …, 2021 - Elsevier
Cardiovascular diseases (CVDs) are one of the leading causes of the most considerable
mortality globally, and it has been tried to find the molecular mechanisms and design new …

[HTML][HTML] Role of extracellular matrix and inflammation in abdominal aortic aneurysm

KL Stepien, K Bajdak-Rusinek, A Fus-Kujawa… - International journal of …, 2022 - mdpi.com
Abdominal aortic aneurysm (AAA) is one of the most dangerous cardiovascular diseases,
occurring mainly in men over the age of 55 years. As it is asymptomatic, patients are …

Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm

HA Cooper, S Cicalese, KJ Preston… - Cardiovascular …, 2021 - academic.oup.com
Abstract Aims Angiotensin II (AngII) is a potential contributor to the development of
abdominal aortic aneurysm (AAA). In aortic vascular smooth muscle cells (VSMCs) …

[HTML][HTML] Dysregulations of key regulators of angiogenesis and inflammation in abdominal aortic aneurysm

D Zalewski, P Chmiel, P Kołodziej, G Borowski… - International Journal of …, 2023 - mdpi.com
Abdominal aortic aneurysm (AAA) is a chronic vascular disease caused by localized
weakening and broadening of the abdominal aorta. AAA is a clearly underdiagnosed …

[HTML][HTML] Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis

Y Ishida, Y Kuninaka, M Nosaka, A Kimura… - Nature …, 2020 - nature.com
Inflammatory mediators such as cytokines and chemokines are crucially involved in the
development of abdominal aortic aneurysm (AAA). Here we report that CaCl2 application …

[HTML][HTML] Sex-related differences of matrix metalloproteinases (MMPs): new perspectives for these biomarkers in cardiovascular and neurological diseases

A Trentini, MC Manfrinato, M Castellazzi… - Journal of Personalized …, 2022 - mdpi.com
It is now established that sex differences occur in clinical manifestation, disease
progression, and prognosis for both cardiovascular (CVDs) and central nervous system …

[HTML][HTML] Neutrophils as regulators and biomarkers of cardiovascular inflammation in the context of abdominal aortic aneurysms

J Klopf, C Brostjan, C Neumayer, W Eilenberg - Biomedicines, 2021 - mdpi.com
Neutrophils represent up to 70% of circulating leukocytes in healthy humans and combat
infection mostly by phagocytosis, degranulation and NETosis. It has been reported that …

Research progress on the pathogenesis of aortic aneurysm and dissection in metabolism

Y Zhou, T Wang, H Fan, S Liu, X Teng, L Shao… - Current Problems in …, 2023 - Elsevier
Aortic aneurysm and dissection are complicated diseases having both high prevalence and
mortality. It is usually diagnosed at advanced stages and posing diagnostic and therapeutic …