[PDF][PDF] Danger signals and inflammaging in osteoarthritis

M Millerand, F Berenbaum, C Jacques - Clin Exp Rheumatol, 2019 - clinexprheumatol.org
Osteoarthritis (OA) is the most common age-related chronic and disabling joint disease.
Long considered to be a “wear and tear” disease, OA is now seen as a low-grade …

Cepharanthine: An update of its mode of action, pharmacological properties and medical applications

C Bailly - Phytomedicine, 2019 - Elsevier
Background Cepharanthine (CEP) is a drug used in Japan since the 1950s to treat a
number of acute and chronic diseases, including treatment of leukopenia, snake bites …

Melatonin: A novel candidate for the treatment of osteoarthritis

Y Zhang, T Liu, H Yang, F He, X Zhu - Ageing research reviews, 2022 - Elsevier
Osteoarthritis (OA), characterized by cartilage erosion, synovium inflammation, and
subchondral bone remodeling, is a common joint degenerative disease worldwide. OA …

[HTML][HTML] Betaine attenuates osteoarthritis by inhibiting osteoclastogenesis and angiogenesis in subchondral bone

W Yajun, C Jin, G Zhengrong, F Chao, H Yan… - Frontiers in …, 2021 - frontiersin.org
Osteoarthritis (OA) is the most common type of arthritis with no effective therapy.
Subchondral bone and overlying articular cartilage are closely associated and function as …

Mechanism of traditional Chinese medicine in treating knee osteoarthritis

M Wang, L Liu, CS Zhang, Z Liao, X Jing… - Journal of pain …, 2020 - Taylor & Francis
Knee osteoarthritis (KOA) is a degenerative disease, making a unique contribution to
chronic pain, edema, and limited mobility of knee joint. Traditional Chinese Medicine (TCM) …

Therapeutic potentials and modulatory mechanisms of fatty acids in bone

M Bao, K Zhang, Y Wei, W Hua, Y Gao, X Li… - Cell …, 2020 - Wiley Online Library
Bone metabolism is a lifelong process that includes bone formation and resorption.
Osteoblasts and osteoclasts are the predominant cell types associated with bone …

Obesity, Metabolic Syndrome, and Osteoarthritis—An Updated Review

SJP Sampath, V Venkatesan, S Ghosh… - Current Obesity …, 2023 - Springer
Abstract Purpose of Review Metabolic syndrome (MetS), also called the 'deadly
quartet'comprising obesity, diabetes, dyslipidemia, and hypertension, has been ascertained …

MCC950, the NLRP3 inhibitor, protects against cartilage degradation in a mouse model of osteoarthritis

B Ni, W Pei, Y Qu, R Zhang, X Chu… - Oxidative Medicine …, 2021 - Wiley Online Library
Osteoarthritis (OA), characterized by chronic systemic low‐level inflammation and cartilage
degeneration, is a type of arthritis closely associated with aging. Inflammation and aging …

[HTML][HTML] Visfatin connection: present and future in osteoarthritis and osteoporosis

E Franco-Trepat, M Guillán-Fresco… - Journal of clinical …, 2019 - mdpi.com
Musculoskeletal pathologies (MSPs) such as osteoarthritis (OA) and osteoporosis (OP), are
a set of disorders that cause severe pain, motion difficulties, and even permanent disability …

[HTML][HTML] Is inflammatory signaling involved in disease-related muscle wasting? Evidence from osteoarthritis, chronic obstructive pulmonary disease and type II …

S Dalle, K Koppo - Experimental gerontology, 2020 - Elsevier
Muscle loss is an important feature that occurs in multiple pathologies including
osteoarthritis (OA), chronic obstructive pulmonary disease (COPD) and type II diabetes …