Musculoskeletal pain is a condition that characterises several diseases and represents a
constantly growing issue with enormous socio-economic burdens, highlighting the …

Chemotherapy-induced neuropathic pain (CINP) is among the most common clinical
complications associated with the use of anti-cancer drugs. CINP occurs in nearly 68.1% of …

Neuromas are a substantial cause of morbidity and reduction in quality of life. This is not
only caused by a disruption in motor and sensory function from the underlying nerve injury …

Orofacial pain is a universal predicament, afflicting millions of individuals worldwide.
Research on the molecular mechanisms of orofacial pain has predominately focused on the …

Temporomandibular disorders (TMD) represent a group of musculoskeletal conditions
involving the temporomandibular joints (TMJ), the masticatory muscles and associated …

Chronic primary orofacial pain (OFP) conditions such as painful temporomandibular
disorders (pTMDs; ie, myofascial pain and arthralgia), idiopathic trigeminal neuralgia (TN) …

Botulinum neurotoxins (BoNTs) are a family of neurotoxins produced by Clostridia and other
bacteria that induce botulism. BoNTs are internalized into nerve terminals at the site of …

Glutamate is the principal excitatory neurotransmitter in the central nervous system. In the
periphery, glutamate acts as a transmitter and involves in the signaling and processing of …

This study evaluates the pharmacological potential of cis-jasmone (CJ) in adult zebrafish
(Danio rerio; aZF). Initially, aZF (n= 6/group) were pretreated (20 µL; po) with CJ (0.1 or 0.3 …

Background: Transient Receptor Potential (TRP) channels are non-selective Ca2+
permeable channels with a wide and dynamic involvement in the perception of …