Since the beautiful images of Santiago Ramón y Cajal provided a first glimpse into the
immense diversity and complexity of cell types found in the cerebral cortex, neuroscience …

The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Ischemic stroke causes neuron loss and long-term functional deficits. Unfortunately, effective
approaches to preserve neurons and promote functional recovery remain unavailable …

Here, we used single-cell RNA sequencing (scRNA-seq), single-cell ATAC sequencing
(scATAC-seq), and single-cell spatial transcriptomics to characterize murine cortical OPCs …

Background Accumulation of amyloid beta, tau hyperphosphorylation, and microglia
activation are the three highly acknowledged pathological factors of Alzheimer's disease …

Schizophrenia is a significant worldwide health concern, affecting over 20 million individuals
and contributing to a potential reduction in life expectancy by up to 14.5 years. Despite its …

Functional implication for myelin regeneration in recovery from ischaemic stroke | Brain | Oxford
Academic Skip to Main Content Advertisement Oxford Academic Journals Books Search Menu …

In vertebrates, oligodendrocytes (OLs) are glial cells of the central nervous system (CNS)
responsible for the formation of the myelin sheath that surrounds the axons of neurons. The …

Oligodendrocyte-lineage cells are central nervous system (CNS) glia that perform multiple
functions including the selective myelination of some but not all axons. During myelination …

Adult oligodendrocyte precursor (or progenitor) cells (OPCs) are the most proliferative cells
in the CNS and constitute approximately 10% of cells in the human brain. 1, 2 Whereas their …