The role of the androgen receptor (AR) in estrogen receptor (ER)-α-positive breast cancer is
controversial, constraining implementation of AR-directed therapies. Using a diverse …

Synthetic progestins (PGs) are a large family of hormones used in continuously growing
amounts in human and animal contraception and medicinal therapies. Because wastewater …

Currently, the presence of endocrine disrupting chemicals (EDCs) in the marine
environment pose а potential risk to both wildlife and human health. The occurrence of …

The application of some hormones in fish production in swamps enhances fish production.
However, in this regard, the critical issue is chemical contamination in water, which affects …

Background: To recognize the action of pharmacologically approved anticancer drugs in
biological systems, information regarding its pharmacokinetics, such as its transport within …

Progestins used in hormonal contraceptives and menopausal hormone therapy (MHT) have
been linked to increased breast cancer risk. Whether the association holds for all progestins …

The release of endocrine-disrupting chemicals (EDCs) into the aquatic environment,
specifically the oceans, is increasing, leading to adverse effects on the marine ecosystem …

Background Traditional approaches to drug development are costly and involve high risks.
The drug repurposing approach can be a valuable alternative to traditional approaches and …

Progestins, synthetic compounds designed to mimic the activity of natural progesterone (P4),
are used globally in menopausal hormone therapy. Although the older progestins …

Herbs and spices have been used throughout human history for their medicinal qualities.
The advent of cheap and readily available medicines have lessened the need for herbs and …