Dengue is a highly endemic infectious disease of the tropical countries and is rapidly
becoming a global burden. It is caused by any of the 4 serotypes of dengue virus and is …

The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

Dengue virus is the pathogenic principle behind several medical conditions. The most
common disease caused by this virus is dengue fever, characterized by high fever and flu …

Dengue is the most prevalent mosquito-borne viral disease worldwide. Yet, there are no
vaccines or specific antivirals available to prevent or treat the disease. Several dengue …

Recombinant protein subunit vaccines are formulated using defined protein antigens that
can be produced in heterologous expression systems. The methylotrophic yeast Pichia …

Dengue is a mosquito-borne disease which is currently an expanding global health
problem. The disease is caused by four closely related viruses, the dengue virus. There are …

ABSTRACT Dengue virus serotype 2 (DENV2) is widespread and responsible for severe
epidemics. While primary DENV2 infections stimulate serotype-specific protective …

Dengue is the most common mosquito-transmitted viral infection for which an improved
vaccine is still needed. Although nonstructural protein-1 (NS1) immunization can protect …

Presumptive treatment of febrile illness patients for malaria remains the norm in endemic
areas of West Africa, and “malaria” remains the top source of health facility outpatient visits …

Abstract Cyclooxygenase-2 (COX-2) is one of the important mediators of inflammation in
response to viral infection, and it contributes to viral replication, for example …