[HTML][HTML] The emerging role of branched-chain amino acids in liver diseases
EKK Lo, Felicianna, JH Xu, Q Zhan, Z Zeng… - Biomedicines, 2022 - mdpi.com
Chronic liver diseases pose a substantial health burden worldwide, with approximately two
million deaths each year. Branched-chain amino acids (BCAAs)—valine, leucine, and …
million deaths each year. Branched-chain amino acids (BCAAs)—valine, leucine, and …
[HTML][HTML] Antioxidant and anti-inflammatory agents in chronic liver diseases: Molecular mechanisms and therapy
Chronic liver disease (CLD) is a continuous process that causes a reduction of liver function
lasting more than six months. CLD includes alcoholic liver disease (ALD), non-alcoholic fatty …
lasting more than six months. CLD includes alcoholic liver disease (ALD), non-alcoholic fatty …
[HTML][HTML] Heterogeneity of hepatocellular carcinoma: from mechanisms to clinical implications
F Safri, R Nguyen, S Zerehpooshnesfchi… - Cancer Gene …, 2024 - nature.com
Hepatocellular Carcinoma (HCC) is one of the most common types of primary liver cancer.
Current treatment options have limited efficacy against this malignancy, primarily owing to …
Current treatment options have limited efficacy against this malignancy, primarily owing to …
[HTML][HTML] Advances in radiotherapy and immunity in hepatocellular carcinoma
Y Yang, L Xiong, M Li, P Jiang, J Wang, C Li - Journal of Translational …, 2023 - Springer
Primary liver cancer is one of the most common malignant tumours worldwide; it caused
approximately 830,000 deaths in 2020. Hepatocellular carcinoma (HCC) is the most …
approximately 830,000 deaths in 2020. Hepatocellular carcinoma (HCC) is the most …
[HTML][HTML] Cellular and molecular biology of cancer stem cells of hepatocellular carcinoma
KS Jeng, CF Chang, IS Sheen, CJ Jeng… - International journal of …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death globally. The
cancer stem cells (CSCs) of HCC are responsible for tumor growth, invasion, metastasis …
cancer stem cells (CSCs) of HCC are responsible for tumor growth, invasion, metastasis …
[HTML][HTML] Cancer cell genetics shaping of the tumor microenvironment reveals myeloid cell-centric exploitable vulnerabilities in hepatocellular carcinoma
CFA Ramirez, D Taranto, M Ando-Kuri… - Nature …, 2024 - nature.com
Myeloid cells are abundant and plastic immune cell subsets in the liver, to which pro-
tumorigenic, inflammatory and immunosuppressive roles have been assigned in the course …
tumorigenic, inflammatory and immunosuppressive roles have been assigned in the course …
A fluorene derivative inhibits human hepatocellular carcinoma cells by ROS-mediated apoptosis, anoikis and autophagy
R Urade, WT Chang, CC Ko, RN Li, HM Yang… - Life Sciences, 2023 - Elsevier
Fluorene was previously reported to have anticancer activity against human cancer cells. In
this study, we examined the in vitro function of 9-methanesulfonylmethylene-2, 3-dimethoxy …
this study, we examined the in vitro function of 9-methanesulfonylmethylene-2, 3-dimethoxy …
A selective androgen receptor modulator, S4, displays robust anti-cancer activity on hepatocellular cancer cells by negatively regulating PI3K/AKT/mTOR signalling …
Hepatocellular carcinoma (HCC) is a major global health problem that often correlates with
poor prognosis. Due to the insufficient therapy options with limited benefits, it is crucial to …
poor prognosis. Due to the insufficient therapy options with limited benefits, it is crucial to …
Imidazopyridine-based kinase inhibitors as potential anticancer agents: A review
F Peytam, Z Emamgholipour, A Mousavi, M Moradi… - Bioorganic …, 2023 - Elsevier
Considering the fundamental role of protein kinases in the mechanism of protein
phosphorylation in critical cellular processes, their dysregulation, especially in cancers, has …
phosphorylation in critical cellular processes, their dysregulation, especially in cancers, has …