Taraxacum mongolicum polysaccharide promotes white adipocyte browning by regulating miR-134-3p via Akt/GSK-3β signalling

X Yue, L Zhong, M Ye, Y Luan, Q Zhang… - International Journal of …, 2024 - Elsevier
In recent years, the incidence of obesity has gradually increased due to high calorie diets
and lack of exercise. Reducing energy intake or increasing energy expenditure is the most …

[HTML][HTML] The Crosstalk between Mesenchymal Stromal/Stem Cells and Hepatocytes in Homeostasis and under Stress

IV Kholodenko, RV Kholodenko… - International Journal of …, 2023 - mdpi.com
Liver diseases, characterized by high morbidity and mortality, represent a substantial
medical problem globally. The current therapeutic approaches are mainly aimed at reducing …

[HTML][HTML] Leptin signaling and leptin resistance

J Liu, F Lai, Y Hou, R Zheng - Medical review, 2022 - degruyter.com
With the prevalence of obesity and associated comorbidities, studies aimed at revealing
mechanisms that regulate energy homeostasis have gained increasing interest. In 1994, the …

Anti-hepatitis B virus activity of lithospermic acid, a polyphenol from Salvia miltiorrhiza, in vitro and in vivo by autophagy regulation

S Zhu, H Wen, W Wang, Y Chen, F Han… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Salvia miltiorrhiza (the roots of S. miltiorrhiza Bunge,
Danshen in Chinese), a traditional Chinese medicine, has been clinically used to prevent …

[HTML][HTML] The mechanism of flavonoids from Cyclocarya paliurus on inhibiting liver cancer based on in vitro experiments and network pharmacology

J Mo, Y Tong, J Ma, K Wang, Y Feng, L Wang… - Frontiers in …, 2023 - frontiersin.org
Introduction: Cyclocarya paliurus (Batal.) Iljinsk., a subtropical tree belonging to the family
Juglandaceae, is rich in polysaccharides, flavonoids, and terpenoids. It has important …

[HTML][HTML] Unraveling the Janus-Faced Role of Autophagy in Hepatocellular Carcinoma: Implications for Therapeutic Interventions

TH Nguyen, TM Nguyen, DTM Ngoc, T You… - International Journal of …, 2023 - mdpi.com
This review aims to provide a comprehensive understanding of the molecular mechanisms
underlying autophagy and mitophagy in hepatocellular carcinoma (HCC). Autophagy is an …

[HTML][HTML] The translational bridge between inflammation and hepatocarcinogenesis

S Gufler, R Seeboeck, C Schatz, J Haybaeck - Cells, 2022 - mdpi.com
Viral infections or persistent alcohol or drug abuse, together with intrinsic factors, lead to
hepatitis, which often ends in the development of liver cirrhosis or hepatocellular carcinoma …

Liver cancer development driven by the AP-1/c-Jun~ Fra-2 dimer through c-Myc

L Bakiri, SC Hasenfuss… - Proceedings of the …, 2024 - National Acad Sciences
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death. HCC incidence
is on the rise, while treatment options remain limited. Thus, a better understanding of the …

[PDF][PDF] RETRACTED: Exosomes From Cancer-Associated Mesenchymal Stem Cells Transmit TMBIM6 to Promote the Malignant Behavior of Hepatocellular Carcinoma …

C Shang, M Ke, L Liu, C Wang, Y Liu, X Zheng - Frontiers in oncology, 2022 - frontiersin.org
Objective Cancer-associated mesenchymal stem cells (MSCs) regulate the progression of
cancers through exosome-delivered components, while few studies are conducted on …

A fluorene derivative inhibits human hepatocellular carcinoma cells by ROS-mediated apoptosis, anoikis and autophagy

R Urade, WT Chang, CC Ko, RN Li, HM Yang… - Life Sciences, 2023 - Elsevier
Fluorene was previously reported to have anticancer activity against human cancer cells. In
this study, we examined the in vitro function of 9-methanesulfonylmethylene-2, 3-dimethoxy …