In recent years, the incidence of obesity has gradually increased due to high calorie diets
and lack of exercise. Reducing energy intake or increasing energy expenditure is the most …

The liver is a complicated heterogeneous organ composed of different cells. Parenchymal
cells called hepatocytes and various nonparenchymal cells, including immune cells and …

This review aims to provide a comprehensive understanding of the molecular mechanisms
underlying autophagy and mitophagy in hepatocellular carcinoma (HCC). Autophagy is an …

Hepatocellular carcinoma (HCC) is the world's third most fatal cancer. Because metabolic
rewiring is a hallmark of HCC, studies into the causes of aberrant glycolysis could provide …

Liver diseases, characterized by high morbidity and mortality, represent a substantial
medical problem globally. The current therapeutic approaches are mainly aimed at reducing …

Uncontrolled chronic inflammation, in most cases due to excessive cytokine signaling
through their receptors, is known to contribute to the development of tumorigenesis …

Abstract Ethnopharmacological relevance The Sanshimao (SSM) formula is an effective
prescription for hepatocellular carcinoma (HCC) therapy in the clinical setting. This …

Abstract Orexin (OX) A and OXB are a pair of neuropeptides secreted by orexin-producing
neurons in the lateral hypothalamus. The orexin system can regulate many physiological …

Background/Aim: Liver cancer is one of the malignancies with the highest mortality-to-
incidence ratio worldwide. Therefore, novel therapeutic approaches are urgently needed …

S-palmitoylation is a reversible protein lipidation that controls the subcellular localization
and function of targeted proteins, including oncogenes such as N-RAS. The …