Insights in Molecular Therapies for Hepatocellular Carcinoma

P Heumann, A Albert, K Gülow, D Tümen, M Müller… - Cancers, 2024 - mdpi.com
Simple Summary Molecular directed therapy for hepatocellular carcinoma (HCC) involves
targeting specific signaling pathways that normally promote cancer cell growth and survival …

Screening immune-related blood biomarkers for DKD-related HCC using machine learning

C Chen, Z Xie, Y Ni, Y He - Frontiers in Immunology, 2024 - frontiersin.org
Background Diabetes mellitus is a significant health problem worldwide, often leading to
diabetic kidney disease (DKD), which may also influence the occurrence of hepatocellular …

Targeting the PI3K/pAKT/mTOR/NF‐κB/FOXO3a signaling pathway for suppressing the development of hepatocellular carcinoma in rats: Role of the natural remedic …

MS Abdel‐Bakky, HA Mohammed… - Environmental …, 2024 - Wiley Online Library
Liver malignancy is well recognized as a prominent health concern, with numerous
treatment options available. Natural products are considered a renewable source, providing …

Effects of LAIR‐1 on hepatocellular carcinoma cell proliferation and invasion via PI3K‐AKT‐mTOR pathway regulation

T Zhou, L Liu, H Lan, D Fang - Immunity, Inflammation and …, 2023 - Wiley Online Library
Introduction Hepatocellular carcinoma (HCC) is one of the common malignant tumors.
Although surgical resection is the best treatment for HCC, many patients with HCC are found …

The combination sorafenib-raloxifene-loratadine as a novel potential therapeutic approach against human liver cancer

F Villarruel-Melquiades, E Hernandez-Gallegos… - in vivo, 2023 - iv.iiarjournals.org
Background/Aim: Liver cancer is one of the malignancies with the highest mortality-to-
incidence ratio worldwide. Therefore, novel therapeutic approaches are urgently needed …

DPY30 knockdown suppresses colorectal carcinoma progression via inducing Raf1/MST2-mediated apoptosis

HF Jiang, WC Su, HX Wang, CY Luo, YT Wang… - Heliyon, 2024 - cell.com
Colorectal Carcinoma (CRC) is one of the most common malignant tumors of the digestive
tract, with a high mortality rate. DPY30 is one of the core subunits of the histone …

Application of the human amniotic membrane as an adjuvant therapy for the treatment of hepatocellular carcinoma

AM Abou-Shanab, OA Gaser, RA Salah, N El-Badri - 2023 - Springer
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related morbidity
and mortality worldwide. Current therapeutic approaches suffer significant side effects and …

Pan‐cancer analysis of DCTN2 and its tumour‐promoting role in HCC by modulating the AKT pathway

S Xu, J Xing, K Li, L Qiao, C Zhang… - Journal of Cellular and …, 2024 - Wiley Online Library
Abstract Dynactin subunit 2 (DCTN2) has been reported to play a role in progression of
several tumours; however, the involvement of DCTN2 in potential mechanism or the tumour …

Extract of Ficus septica modulates apoptosis and migration in human oral squamous cell carcinoma cells

LY Bai, KLH Wu, CF Chiu, HC Chao… - Environmental …, 2023 - Wiley Online Library
According to the alarming statistical analysis of global cancer, there are over 19 million new
diagnoses and more than 10 million deaths each year. One such cancer is the oral …

[HTML][HTML] High Ki67 Gene Expression Is Associated With Aggressive Phenotype in Hepatocellular Carcinoma

V Ramos-Santillan, M Oshi, E Nelson… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Background Hepatocellular carcinoma (HCC) with high Ki67 protein expression, the most
commonly used cell proliferation marker, is associated with an aggressive biologic …