[HTML][HTML] The repurposing of non-peptide neurokinin-1 receptor antagonists as antitumor drugs: An urgent challenge for aprepitant

R Coveñas, FD Rodríguez, P Robinson… - International journal of …, 2023 - mdpi.com
The substance P (SP)/neurokinin-1 receptor (NK-1R) system is involved in cancer
progression. NK-1R, activated by SP, promotes tumor cell proliferation and migration …

[HTML][HTML] Subtype Transdifferentiation in Human Cancer: The Power of Tissue Plasticity in Tumor Progression

M Fedele, L Cerchia, S Battista - Cells, 2024 - mdpi.com
The classification of tumors into subtypes, characterized by phenotypes determined by
specific differentiation pathways, aids diagnosis and directs therapy towards targeted …

Immunosuppressive role of BDNF in therapy‐induced neuroendocrine prostate cancer

YN Liu, WY Chen, MK Liu, HL Yeh… - Molecular …, 2024 - Wiley Online Library
Prostate stromal cells play a crucial role in the promotion of tumor growth and immune
evasion in the tumor microenvironment (TME) through intricate molecular alterations in their …

[HTML][HTML] Targeting Key Players of Neuroendocrine Differentiation in Prostate Cancer

I Zamora, MR Freeman, IJ Encío, M Rotinen - International Journal of …, 2023 - mdpi.com
Neuroendocrine prostate cancer (NEPC) is a highly aggressive subtype of prostate cancer
(PC) that commonly emerges through a transdifferentiation process from prostate …

Targeting key players of neuroendocrine differentiation in prostate cancer

I Zamora Álvarez, MR Freeman… - … Sciences 2023, 24 …, 2023 - academica-e.unavarra.es
Neuroendocrine prostate cancer (NEPC) is a highly aggressive subtype of prostate cancer
(PC) that commonly emerges through a transdifferentiation process from prostate …