Hallmarks of cancer—the new testament

SS Senga, RP Grose - Open biology, 2021 - royalsocietypublishing.org
Diagnosis and treatment of disease demand a sound understanding of the underlying
mechanisms, determining any Achilles' heel that can be targeted in effective therapies …

The microbiome and gynaecological cancer development, prevention and therapy

P Łaniewski, ZE Ilhan, MM Herbst-Kralovetz - Nature Reviews Urology, 2020 - nature.com
The female reproductive tract (FRT), similar to other mucosal sites, harbours a site-specific
microbiome, which has an essential role in maintaining health and homeostasis. In the …

The role of the microbiota in infectious diseases

J Libertucci, VB Young - Nature microbiology, 2019 - nature.com
The human body is colonized by a diverse community of microorganisms collectively
referred to as the microbiota. Here, we describe how the human microbiota influences …

The vaginal microbiota, human papillomavirus and cervical dysplasia: a systematic review and network meta‐analysis

J Norenhag, J Du, M Olovsson… - … Journal of Obstetrics …, 2020 - Wiley Online Library
Background Persistent infection with high‐risk human papillomavirus can lead to cervical
dysplasia and cancer. Recent studies have suggested associations between the …

Vaginal microbiome and cervical cancer

M Kyrgiou, AB Moscicki - Seminars in Cancer Biology, 2022 - Elsevier
The female reproductive tract, similar to other mucosal sites, harbors a specific microbiome
commonly dominated by Lactobacillus species (spp.), which has an essential role in …

Vaginal dysbiosis and the risk of human papillomavirus and cervical cancer: systematic review and meta-analysis

N Brusselaers, S Shrestha, J Van De Wijgert… - American journal of …, 2019 - Elsevier
Objective The vaginal microbiota proposedly influence the association between human
papillomavirus and cervical cancer. Our aim was to assess whether vaginal dysbiosis affects …

Bacterial vaginosis and health-associated bacteria modulate the immunometabolic landscape in 3D model of human cervix

P Łaniewski, MM Herbst-Kralovetz - npj Biofilms and Microbiomes, 2021 - nature.com
Bacterial vaginosis (BV) is an enigmatic polymicrobial condition characterized by a
depletion of health-associated Lactobacillus and an overgrowth of anaerobes. Importantly …

The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions

A Mitra, DA MacIntyre, G Ntritsos, A Smith… - Nature …, 2020 - nature.com
Emerging evidence suggests associations between the vaginal microbiota (VMB)
composition, human papillomavirus (HPV) infection, and cervical intraepithelial neoplasia …

The role of the cervicovaginal microbiome on the genesis and as a biomarker of premalignant cervical intraepithelial neoplasia and invasive cervical cancer

G Curty, PS de Carvalho, MA Soares - International journal of molecular …, 2019 - mdpi.com
The microbiome is able to modulate immune responses, alter the physiology of the human
organism, and increase the risk of viral infections and development of diseases such as …

Interplay among vaginal microbiome, immune response and sexually transmitted viral infections

MG Torcia - International journal of molecular sciences, 2019 - mdpi.com
The vaginal ecosystem is important for women's health and for a successful reproductive life,
and an optimal host-microbial interaction is required for the maintenance of eubiosis. The …