Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based approaches
J Dey, SR Mahapatra, PK Singh… - Immunologic …, 2023 - Springer
Acinetobacter baumannii is one of the major pathogenic ESKAPE bacterium, which is
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …
Mechanistic inhibition of gastric cancer-associated bacteria Helicobacter pylori by selected phytocompounds: A new cutting-edge computational approach
Background Helicobacter pylori (H. pylori) is a persistent bacterial inhabitant in the stomachs
of approximately half the global populace. This bacterium is directly linked to chronic …
of approximately half the global populace. This bacterium is directly linked to chronic …
MERS virus spike protein HTL-epitopes selection and multi-epitope vaccine design using computational biology
MERS-CoV, a zoonotic virus, poses a serious threat to public health globally. Thus, it is
imperative to develop an effective vaccination strategy for protection against MERS-CoV …
imperative to develop an effective vaccination strategy for protection against MERS-CoV …
Translational protein RpsE as an alternative target for novel nucleoside analogues to treat MDR Enterobacter cloacae ATCC 13047: network analysis and molecular …
The pathogenic Enterobacter cloacae subsp. cloacae str. ATCC 13047 has contemporarily
emerged as a multi-drug resistant strain. To formulate an effective treatment option …
emerged as a multi-drug resistant strain. To formulate an effective treatment option …
[HTML][HTML] A designed peptide-based vaccine to combat Brucella melitensis, B. suis and B. abortus: Harnessing an epitope mapping and immunoinformatics approach
H Tarrahimofrad, J Zamani, MR Hamblin… - Biomedicine & …, 2022 - Elsevier
Vaccines against Brucella abortus, B. melitensis and B. suis have been based on weakened
or killed bacteria, however there is no recombinant vaccine for disease prevention or …
or killed bacteria, however there is no recombinant vaccine for disease prevention or …
Computational design of a multi-epitope vaccine candidate against Langya henipavirus using surface proteins
Abstract In July 2022, Langya henipavirus (LayV) was identified in febrile patients in China.
There is currently no approved vaccine against this virus. Therefore, this research aimed to …
There is currently no approved vaccine against this virus. Therefore, this research aimed to …
Advances in computational and bioinformatics tools and databases for designing and developing a multi-epitope-based peptide vaccine
A vaccine is defined as a biologic preparation that trains the immune system, boosts
immunity, and protects against a deadly microbial infection. They have been used for …
immunity, and protects against a deadly microbial infection. They have been used for …
Designing a bioadjuvant candidate vaccine targeting infectious bursal disease virus (IBDV) using viral VP2 fusion and chicken IL-2 antigenic epitope: A bioinformatics …
S Soleymani, F Janati-Fard… - Computers in Biology and …, 2023 - Elsevier
Abstract Infectious Bursal Disease (IBD) is a common and contagious viral infection that
significantly affects the poultry industry. This severely suppresses the immune system in …
significantly affects the poultry industry. This severely suppresses the immune system in …
Proteomics-based vaccine targets annotation and design of multi-epitope vaccine against antibiotic-resistant Streptococcus gallolyticus
P Chao, X Zhang, L Zhang, A Yang, Y Wang… - Scientific Reports, 2024 - nature.com
Streptococcus gallolyticus is a non-motile, gram-positive bacterium that causes infective
endocarditis. S. gallolyticus has developed resistance to existing antibiotics, and no vaccine …
endocarditis. S. gallolyticus has developed resistance to existing antibiotics, and no vaccine …
Use of immunoinformatics and the simulation approach to identify Helicobacter pylori epitopes to design a multi-epitope subunit vaccine for B- and T-cells
ZA Chaleshtori, AA Rastegari, H Nayeri, A Doosti - BMC biotechnology, 2023 - Springer
Background Helicobacter pylori cause a variety of gastric malignancies, gastric ulcers, and
cause erosive diseases. The extreme nature of the bacterium and the implantation of this …
cause erosive diseases. The extreme nature of the bacterium and the implantation of this …