Congenital anomalies of the kidneys and urinary tracts (CAKUT) are disorders caused by
defects in the development of the kidneys and their outflow tracts. The formation of the …

Assisted reproductive technology (ART) includes fertility treatment in which either eggs or
embryos are handled outside a female's body to promote successful pregnancies and …

Societal changes and the increasing desire and opportunity to preserve fertility have
increased the demand for effective assisted reproductive technologies (ART) and have …

Epigenetics is the branch of genetics that studies the different mechanisms that influence
gene expression without direct modification of the DNA sequence. An ever-increasing …

Since the birth of Louise Brown in 1978 via IVF, reproductive specialists have acquired
enormous knowledge and refined several procedures, which are nowadays applied in …

Since the birth of Louise Joy Brown, the first baby conceived via in vitro fertilization, more
than 9 million children have been born worldwide using assisted reproductive technologies …

Mammalian oocyte maturation and embryo development are unique biological processes
regulated by various modifications. Since de novo mRNA transcription is absent during …

The epigenome is dynamic and forged by epigenetic mechanisms, such as DNA
methylation, histone modifications, chromatin remodeling, and non-coding RNA species …

Recurrent implantation failure (RIF) is a poorly defined clinical scenario marked by failure to
achieve pregnancy after multiple embryo transfers. The causes and definitions of …

Assisted reproductive technology may influence epigenetic signature as the procedures
coincide with the extensive epigenetic modification occurring from fertilization to embryo …