Interactions between gut microbiota and polyphenols: A mechanistic and metabolomic review

H Cheng, D Zhang, J Wu, J Liu, Y Zhou, Y Tan, W Feng… - Phytomedicine, 2023 - Elsevier
Background Polyphenols are a class of naturally sourced compounds with widespread
distribution and an extensive array of bioactivities. However, due to their complex …

[HTML][HTML] Function of Akkermansia muciniphila in type 2 diabetes and related diseases

J Li, G Yang, Q Zhang, Z Liu, X Jiang… - Frontiers in Microbiology, 2023 - frontiersin.org
The prevalence of type 2 diabetes (T2D) is increasing worldwide, with many patients
developing long-term complications that affect their cardiovascular, urinary, alimentary, and …

Shatianyu (Citrus grandis L. Osbeck) Flavonoids and Dietary Fiber in Combination Are More Effective Than Individually in Alleviating High-Fat-Diet-Induced …

M Deng, S Zhang, L Dong, F Huang, X Jia… - Journal of Agricultural …, 2022 - ACS Publications
This study was aimed at exploring the separate and combined anti-hyperlipidemic effect of
Shatianyu (Citrus grandis L. Osbeck) flavonoids (SPFEs) and DF (SPDF) on HFD-fed mice …

Preventive effects of apple polyphenol extract on high-fat-diet-induced hepatic steatosis are related to the regulation of hepatic lipid metabolism, autophagy, and gut …

Y Yin, Y Xie, Z Wu, Q Qian, H Yang… - Journal of Agricultural …, 2023 - ACS Publications
Our previous study confirmed that the ameliorated effects of an intervention with an apple
polyphenol extract (APE) on hepatic steatosis induced by a high-fat diet (HFD) are …

Prevention of High-Fat-Diet-Induced Dyslipidemia by Lactobacillus plantarum LP104 through Mediating Bile Acid Enterohepatic Axis Circulation and Intestinal Flora

Y Wang, X Xing, Y Ma, Y Fan, Y Zhang… - Journal of Agricultural …, 2023 - ACS Publications
This work aimed to investigate the alleviative mechanism of Lactobacillus plantarum LP104
(LP104) isolated from kimchi on high-fat-diet-induced dyslipidemia by targeting the intestinal …

Gut microbiota-metabolic axis insight into the hyperlipidemic effect of lotus seed resistant starch in hyperlipidemic mice

H Zeng, S He, Z Xiong, J Su, Y Wang, B Zheng… - Carbohydrate …, 2023 - Elsevier
We investigated the hyperlipidemic effect of different doses of lotus seed resistant starch
(low-, medium and high-dose LRS, named as LLRS, MLRS and HLRS, respectively) in …

Dietary isoquercetin reduces hepatic cholesterol and triglyceride in NAFLD mice by modulating bile acid metabolism via intestinal FXR-FGF15 signaling

C Zhang, Z Shi, H Lei, F Wu, C Chen… - Journal of Agricultural …, 2023 - ACS Publications
Isoquercetin, a monosaccharide flavonoid, was recently reported to have significant
amelioration effects on high-fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD) …

Bile acid metabolism and signaling: emerging pharmacological targets of dietary polyphenols

KM Tveter, E Mezhibovsky, Y Wu… - Pharmacology & …, 2023 - Elsevier
Beyond their role as emulsifiers of lipophilic compounds, bile acids (BAs) are signaling
endocrine molecules that show differential affinity and specificity for a variety of canonical …

The Ameliorating Effects of Apple Polyphenol Extract on High-Fat-Diet-Induced Hepatic Steatosis Are SIRT1-Dependent: Evidence from Hepatic-Specific SIRT1 …

Y Yin, D Li, F Liu, X Wang, Y Cui, S Li… - Journal of Agricultural …, 2022 - ACS Publications
Apple polyphenol extract (APE) has been reported to possess protective effects against
hepatic steatosis. To explore whether APE-induced alleviation of hepatic steatosis is SIRT1 …

Apple polyphenol extract modulates bile acid metabolism and gut microbiota by regulating the circadian rhythms in daytime-restricted high fat diet feeding C57BL/6 …

Y Cui, Y Yin, S Li, Z Wu, Y Xie, Q Qian, H Yang, X Li - Food & Function, 2022 - pubs.rsc.org
The homeostasis of circadian clock linked to bile acid (BA) metabolism and gut microbiota
has profound benefits in maintaining the health status of the host. The aim of this study was …