Shortening synthetic routes to small molecule active pharmaceutical ingredients employing biocatalytic methods
S Simić, E Zukić, L Schmermund, K Faber… - Chemical …, 2021 - ACS Publications
Biocatalysis, using enzymes for organic synthesis, has emerged as powerful tool for the
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …
[HTML][HTML] Acquired von Willebrand syndrome: focused for hematologists
M Franchini, PM Mannucci - Haematologica, 2020 - ncbi.nlm.nih.gov
The acquired von Willebrand syndrome (AvWS) is a rare bleeding disorder with laboratory
findings similar to those of inherited von Willebrand disease. However, unlike the inherited …
findings similar to those of inherited von Willebrand disease. However, unlike the inherited …
Perioperative considerations in management of the severely bleeding coagulopathic patient
G Erdoes, D Faraoni, A Koster, ME Steiner… - …, 2023 - pubs.asahq.org
Inherited and acquired coagulopathy are frequently associated with major bleeding in
severe trauma, cardiac surgery with cardiopulmonary bypass, and postpartum hemorrhage …
severe trauma, cardiac surgery with cardiopulmonary bypass, and postpartum hemorrhage …
Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI
JJ Molina, KN Kohler, C Gager, MJ Andersen… - Nature …, 2024 - nature.com
Catheter-associated urinary tract infections (CAUTIs) are amongst the most common
nosocomial infections worldwide and are difficult to treat partly due to development of …
nosocomial infections worldwide and are difficult to treat partly due to development of …
Tranexamic acid dose–response relationship for antifibrinolysis in postpartum haemorrhage during Caesarean delivery: TRACES, a double-blind, placebo-controlled …
AS Ducloy-Bouthors, S Gilliot, M Kyheng… - British Journal of …, 2022 - Elsevier
Background The optimal dose of tranexamic acid to inhibit hyperfibrinolysis in postpartum
haemorrhage is unclear. Tranexamic Acid to Reduce Blood Loss in Hemorrhagic Cesarean …
haemorrhage is unclear. Tranexamic Acid to Reduce Blood Loss in Hemorrhagic Cesarean …
Erythrocyte Membrane‐Coated Invisible Acoustic‐Sensitive Nanoparticle for Inducing Tumor Thrombotic Infarction by Precisely Damaging Tumor Vascular …
H Xie, W Li, H Liu, Y Chen, M Ma, Y Wang, Y Luo… - Small, 2022 - Wiley Online Library
Selective induction of tumor thrombus infarction is a promising antitumor strategy. Non‐
persistent embolism due to non‐compacted thrombus and activated fibrinolytic system within …
persistent embolism due to non‐compacted thrombus and activated fibrinolytic system within …
Hemorrhage in essential thrombocythemia or polycythemia vera: epidemiology, location, risk factors, and lessons learned from the literature
C Nicol, K Lacut, B Pan-Petesch… - Thrombosis and …, 2021 - thieme-connect.com
Hemorrhage is a well-known complication of essential thrombocythemia (ET) and
polycythemia vera (PV), but evidence-based data on its management and prevention are …
polycythemia vera (PV), but evidence-based data on its management and prevention are …
Absence of hyperfibrinolysis may explain lack of efficacy of tranexamic acid in hypoproliferative thrombocytopenia
A Ilich, TB Gernsheimer, DJ Triulzi, H Herren… - Blood …, 2023 - ashpublications.org
Abstract The American Trial Using Tranexamic Acid (TXA) in Thrombocytopenia (A-TREAT,
NCT02578901) demonstrated no superiority of TXA over placebo in preventing World …
NCT02578901) demonstrated no superiority of TXA over placebo in preventing World …
[HTML][HTML] Microcluster colloidosomes for hemostat delivery into complex wounds: A platform inspired by the attack action of torpedoes
B Lu, E Hu, R Xie, K Yu, F Lu, R Bao, C Wang, G Lan… - Bioactive Materials, 2022 - Elsevier
Complex yet lethal wounds with uncontrollable bleeding hinder conventional hemostats
from clotting blood at the source or deep sites of injury vasculature, thereby causing massive …
from clotting blood at the source or deep sites of injury vasculature, thereby causing massive …
Longitudinal trends of patient demographics and morbidity of different approaches in lumbar interbody fusion: an analysis using the American College of Surgeons …
L Oezel, I Okano, AP Hughes, M Sarin, J Shue… - World Neurosurgery, 2022 - Elsevier
Objective The aims of this study were to determine the time trend of demographics,
complications, and outcomes for patients undergoing posterior lumbar interbody …
complications, and outcomes for patients undergoing posterior lumbar interbody …