Acute kidney injury occurs with kidney transplantation and too frequently progresses to the
clinical diagnosis of delayed graft function (DGF). Poor kidney function in the first week of …

The introduction of insulin therapy for the management of diabetes mellitus is arguably the
greatest milestone in the history of modern medicine. β‐cell replacement therapy is the only …

The current organ shortage has made utilization of organs from less-than-ideal donors more
common. Although several transplant centers use kidneys from non-heart-beating donors …

Background. Organ cryopreservation is hindered by ice inflicted damage. Nonfreezing
preservation of livers at subzero temperatures might offer advantages over current …

Background & Aims Hypothermic oxygenated machine perfusion (HOPE) is a promising
technique for providing oxygen to the liver during graft preservation; however, because of …

Liver transplantation is often the only effective treatment for end stage liver diseases
resulting from cirrhosis, hepatitis, progressive jaundice, and biliary atresia. Hypothermic …

Background. Although hypothermic machine perfusion (HMP) preservation has been shown
to improve organ function and to expand the organ donor pool, problems still exist with the …

Clinical outcomes of pancreas transplantation were superior to that of islet transplantation
until the introduction of the Edmonton protocol. Significant advances in islet isolation and …

Vitrification of endothelial cells (MHECT-5) has not previously been compared with
controlled slow freezing methods under standardized conditions. To identify the best …

The development of effective preservation and long-term storage techniques is a critical
requirement for the successful clinical and commercial application of emerging cell-based …