Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …

Cardiovascular disease (CVD) has overtaken infectious illnesses as the leading cause of
mortality and disability worldwide. The pathology that underpins CVD is atherosclerosis …

Aortic dissection (AD) presents a medical challenge for clinicians. Here, to determine the
role of a novel small non-coding piRNA-823 (piR-823) in AD, murine and human aorta from …

Cholesterol levels are an initiating risk factor for atherosclerosis. Many genes play a central
role in cholesterol synthesis, including HMGCR, SQLE, HMGCS1, FDFT1, LSS, MVK, PMK …

Malonylation is a recently identified post-translational modification with malonyl-coenzyme A
as the donor. It conserved both in prokaryotes and eukaryotes. Recent advances in the …

Long noncoding RNAs (lncRNAs) are important regulators of various cellular functions.
Recent studies have shown that a novel lncRNA termed Punisher is highly expressed in …

Oral gene therapy has emerged as a potential optimal treatment for ulcerative colitis (UC).
Nucleic acid drugs possessing versatility can not only inhibit inflammation but realize colon …

Background Aortic dissection (AD) is a lethal cardiac disorder and one of the most
concerning cardiovascular diseases (CVDs). Increasing evidence indicates that human …

Angiogenesis is a key process in organ and tissue morphogenesis, as well as growth during
human development, and is coordinated by pro-and anti-angiogenic factors. When this …

Abstract Background Ginsenoside Rg2 (Rg2) has a variety of pharmacological activities and
provides benefits during inflammation, cancer, and other diseases. However, there are no …