Roles of Pseudomonas aeruginosa siderophores in interaction with prokaryotic and eukaryotic organisms

GJ Jeong, F Khan, N Tabassum, DM Jo, WK Jung… - Research in …, 2024 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen that produces two types of
siderophores, pyoverdine and pyochelin, that play pivotal roles in iron scavenging from the …

Late-stage diversification of bacterial natural products through biocatalysis

J Lazic, V Filipovic, L Pantelic, J Milovanovic… - … in Bioengineering and …, 2024 - frontiersin.org
Bacterial natural products (BNPs) are very important sources of leads for drug development
and chemical novelty. The possibility to perform late-stage diversification of BNPs using …

Synthetic Peptides Capable of Potent Multigroup Staphylococcal Quorum Sensing Activation and Inhibition in Both Cultures and Biofilm Communities

EL Eisenbraun, TD Vulpis, BN Prosser… - Journal of the …, 2024 - ACS Publications
The pathogen Staphylococcus epidermidis uses a chemical signaling process, ie, quorum
sensing (QS), to form robust biofilms and cause human infection. Many questions remain …

Chemical Modification of a Bacterial Siderophore by a Competitor in Dual‐Species Biofilms

S Uzi‐Gavrilov, Z Tik, O Sabti… - Angewandte Chemie, 2023 - Wiley Online Library
Chemical communication between competing bacteria in multi‐species environments often
enables both species to adapt and survive, and perhaps even thrive. P. aeruginosa and S …

Wound Dressing Based on Silver Nanoparticle Embedded Wool Keratin Electrospun Nanofibers Deposited on Cotton Fabric: Preparation, Characterization …

MM Hassan, K Heins, H Zheng - ACS Applied Bio Materials, 2024 - ACS Publications
Wool keratin (WK) protein is attractive for wound dressing and biomedical applications due
to its excellent biodegradability, cytocompatibility, and wound-healing properties. In this …

Bacterial pneumonia-induced shedding of epithelial heparan sulfate inhibits the bactericidal activity of cathelicidin in a murine model

EP Zehr, CL Erzen, K Oshima… - … of Physiology-Lung …, 2024 - journals.physiology.org
Bacterial pneumonia is a common clinical syndrome leading to significant morbidity and
mortality worldwide. In the current study, we investigate a novel, multidirectional relationship …

Siderophore specificities of the Pseudomonas aeruginosa TonB‐dependent transporters ChtA and ActA

V Will, V Gasser, L Kuhn, S Fritsch, DE Heinrichs… - FEBS …, 2023 - Wiley Online Library
Iron is an essential nutrient for the survival and virulence of Pseudomonas aeruginosa. The
pathogen expresses at least 15 different iron‐uptake pathways, the majority involving small …

Staphylococcus aureus in Polymicrobial Skinand Soft Tissue Infections: Impact of Inter-Species Interactionsin Disease Outcome

F Mariani, EM Galvan - Antibiotics, 2023 - mdpi.com
Polymicrobial biofilms provide a complex environment where co-infecting microorganisms
can behave antagonistically, additively, or synergistically to alter the disease outcome …

Experimentally evolved Staphylococcus aureus shows increased survival in the presence of Pseudomonas aeruginosa by acquiring mutations in the amino acid …

AM Alexander, JM Luu, V Raghuram… - …, 2024 - microbiologyresearch.org
When cultured together under standard laboratory conditions Pseudomonas aeruginosa has
been shown to be an effective inhibitor of Staphylococcus aureus. However, P. aeruginosa …

[HTML][HTML] Autolysis of Pseudomonas aeruginosa Quorum-Sensing Mutant Is Suppressed by Staphylococcus aureus through Iron-Dependent Metabolism

SY Choi, IY Chung, HW Bae, YH Cho - Journal of Microbiology …, 2024 - ncbi.nlm.nih.gov
Microorganisms usually coexist as a multifaceted polymicrobial community in the natural
habitats and at mucosal sites of the human body. Two opportunistic human pathogens …