Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Few among the millions of fungal species fulfill four basic conditions necessary to infect
humans: high temperature tolerance, ability to invade the human host, lysis and absorption …

Fungi must meet four criteria to infect humans: growth at human body temperatures,
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …

Aspergillus species are globally ubiquitous saprophytes found in a variety of ecological
niches. Almost 200 species of aspergilli have been identified, less than 20 of which are …

Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Respiratory fungal infection is a severe clinical problem, especially in patients with
compromised immune functions. Aspergillus, Cryptococcus, Pneumocystis, and endemic …

Aspergillus fumigatus is an opportunistic pathogen that causes 90% of invasive aspergillosis
(IA) due to Aspergillus genus, with a 50–95% mortality rate. It has been postulated that …

The genus Aspergillus contains etiologic agents of aspergillosis. The clinical manifestations
of the disease range from allergic reaction to invasive pulmonary infection. Among the …

Aspergillus flavus is a representative fungal species in the Aspergillus section Flavi and has
been used as a model system to gain insights into fungal development and toxin production …

It has been nearly a decade since caspofungin was approved for clinical use as the first
echinocandin class antifungal agent, followed by micafungin and anidulafungin. The …