Triptolide and celastrol are predominantly active natural products isolated from the
medicinal plant Tripterygium wilfordii Hook F. These compounds exhibit similar …

Rheumatoid arthritis (RA), a chronic and joint-related autoimmune disease, results in
immune dysfunction and destruction of joints and cartilages. Small molecules and biological …

Background The epidemiology of drug-induced liver injury (DILI) in China has rarely been
studied before. The aim of the present study was to determine the etiology of DILI in a …

Rheumatoid arthritis (RA) is a severe systemic inflammatory disease. It is often associated
with serious cartilage destruction and massive inflammatory infiltration, which might …

This study aimed to investigate the oxidative stress in human osteoarthritis (OA)
chondrocytes and the antioxidant effect of angelica sinensis polysaccharide (ASP) on it …

The objective of this present study was to develop and evaluate the triptolide-loaded
nanostructured lipid carriers (TPL-NLCs) for transdermal drug delivery system (TDDS). TPL …

To evaluate the effect of apigenin (AP) on arthritis in rats stimulated by Freund's complete
adjuvant (FCA) was the main purpose of the investigation. Arthritis model was established …

Abstract Aim Solid lipid nanoparticles (SLNs) are novel drug delivery system for drug
targeting in various routs of administration such as parenteral, oral, ophthalmic and topical …

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial joint
inflammation and cartilage and bone tissue destruction. Although there exist some treatment …

Triptolide is the major active ingredient of Tripterygium Glycosides (TG), a traditional
Chinese medicine with very potent anti-inflammatory effects and has been used in China for …