The progression of cancer involves a critical step in which malignant cells escape from
control by the immune system. Antineoplastic agents are particularly efficient when they …

Despite the importance of chemotherapy-associated adverse events in oncology practice
and the broad range of interventions available to mitigate them, limited systematic efforts …

Improving the prognosis for patients with metastatic HR+/HER2-breast cancer remains an
unmet need. Patients with tumors that have progressed on endocrine therapy and/or are not …

Peptide‐based supramolecular therapeutics (PST) refer to those theranostic nanomedicines
based on peptide or peptide derivatives self‐assembly that are constructed in vitro or in vivo …

Paraptosis is a non‐apoptotic and caspase‐independent programmed cell death that can
trigger immunogenic cell death (ICD) in tumor cells, representing a potent tactic to overcome …

Cytotoxicity (ie cell death) is the core mechanism by which chemotherapy induces its anti-
cancer effects. Unfortunately, this same mechanism underpins the collateral damage it …

Autophagy is a highly conserved, lysosome-dependent biological mechanism involved in
the degradation and recycling of cellular components. There is growing evidence that …

Despite significant advances in cancer therapeutics, chemotherapy remains the cornerstone
of treatment for many tumors. Importantly, however, chemotherapy-induced toxicity …

Nanomaterials' application in cancer therapy has been driven by their ability to encapsulate
chemotherapeutic drugs as well as to reach the tumor site. Nevertheless, nanomedicines' …

Purpose Limited knowledge is available on the incidence of febrile neutropenia (FN) in
intermediate-risk patients and the rationale for use of granulocyte colony-stimulating factor …