SARS-CoV-2 mutations and their viral variants

B Cosar, ZY Karagulleoglu, S Unal, AT Ince… - Cytokine & growth factor …, 2022 - Elsevier
Mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occur
spontaneously during replication. Thousands of mutations have accumulated and continue …

Fast-spreading SARS-CoV-2 variants: challenges to and new design strategies of COVID-19 vaccines

W Zhou, W Wang - Signal transduction and targeted therapy, 2021 - nature.com
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is still threatening global health. According to the latest data, the number of …

The biological functions and clinical significance of SARS-CoV-2 variants of corcern

H Akkız - Frontiers in medicine, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuing to evolve,
emerging novel variants with spike protein mutations. Although most mutations emerged in …

[HTML][HTML] Emergence in late 2020 of multiple lineages of SARS-CoV-2 Spike protein variants affecting amino acid position 677

EB Hodcroft, DB Domman, DJ Snyder, KY Oguntuyo… - MedRxiv, 2021 - ncbi.nlm.nih.gov
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) plays
critical roles in host cell entry. Non-synonymous substitutions affecting S are not uncommon …

[HTML][HTML] SARS-CoV-2 new variants: Characteristic features and impact on the efficacy of different vaccines

A Khan, T Khan, S Ali, S Aftab, Y Wang… - Biomedicine & …, 2021 - Elsevier
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its
new variants reported in different countries have posed a serious threat to human health and …

Microfluidic affinity selection of active SARS-CoV-2 virus particles

SST Gamage, TN Pahattuge, H Wijerathne… - Science …, 2022 - science.org
We report a microfluidic assay to select active severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) viral particles (VPs), which were defined as intact particles with …

[HTML][HTML] Sequence analysis of 20,453 severe acute respiratory syndrome coronavirus 2 genomes from the Houston metropolitan area identifies the emergence and …

SW Long, RJ Olsen, PA Christensen, S Subedi… - The American journal of …, 2021 - Elsevier
Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic, there has been international concern about the emergence of virus variants with …

SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts

RN Tasakis, G Samaras, A Jamison, M Lee, A Paulus… - PLoS …, 2021 - journals.plos.org
Since the first case of COVID-19 in December 2019 in Wuhan, China, SARS-CoV-2 has
spread worldwide and within a year and a half has caused 3.56 million deaths globally. With …

Distinct patterns of emergence of SARS-CoV-2 spike variants including N501Y in clinical samples in Columbus Ohio

H Tu, MR Avenarius, L Kubatko, M Hunt, X Pan, P Ru… - BioRxiv, 2021 - biorxiv.org
Following the worldwide emergence of the p. Asp614Gly shift in the Spike (S) gene of SARS-
CoV-2, there have been few recurring pathogenic shifts occurring during 2020, as assessed …

Interspecies transmission of SARS CoV-2 with special emphasis on viral mutations and ACE-2 receptor homology roles

ME Hamdy, AH El Deeb, NM Hagag… - … journal of veterinary …, 2023 - Taylor & Francis
ABSTRACT COVID-19 outbreak was first reported in 2019, Wuhan, China. The spillover of
the disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) …