Synergistic power of genomic selection, assisted reproductive technologies, and gene editing to drive genetic improvement of cattle

ML Mueller, AL Van Eenennaam - CABI Agriculture and Bioscience, 2022 - Springer
Genetic improvement of cattle around the globe has been, and will continue to be, an
important driver of animal agriculture sustainability. There are several reproductive and …

Genome editing approaches to augment livestock breeding programs

TF Bishop, AL Van Eenennaam - Journal of Experimental …, 2020 - journals.biologists.com
The prospect of genome editing offers a number of promising opportunities for livestock
breeders. Firstly, these tools can be used in functional genomics to elucidate gene function …

Donor-derived spermatogenesis following stem cell transplantation in sterile NANOS2 knockout males

M Ciccarelli, MI Giassetti, D Miao… - Proceedings of the …, 2020 - National Acad Sciences
Spermatogonial stem cell transplantation (SSCT) is an experimental technique for transfer of
germline between donor and recipient males that could be used as a tool for biomedical …

CRISPR-based gene drives for pest control

GR McFarlane, CBA Whitelaw, SG Lillico - Trends in biotechnology, 2018 - cell.com
Clustered regularly interspaced short palindromic repeats (CRISPR)-based gene drives
(GDs) could be used to spread desirable genetic elements through wild populations. With …

Review of injection techniques for spermatogonial stem cell transplantation

M Gul, S Hildorf, L Dong, J Thorup… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND Although the prognosis of childhood cancer survivors has increased
dramatically during recent years, chemotherapy and radiation treatments for cancer and …

[HTML][HTML] Single-cell RNA sequencing uncovers dynamic roadmap and cell-cell communication during buffalo spermatogenesis

L Huang, J Zhang, P Zhang, X Huang, W Yang, R Liu… - Iscience, 2023 - cell.com
Spermatogenesis carries the task of precise intergenerational transmission of genetic
information from the paternal genome and involves complex developmental processes …

Progress and opportunities through use of genomics in animal production

HE Jones, PB Wilson - Trends in Genetics, 2022 - cell.com
The rearing of farmed animals is a vital component of global food production systems, but its
impact on the environment, human health, animal welfare, and biodiversity is being …

On-farm livestock genome editing using cutting edge reproductive technologies

GR McFarlane, HA Salvesen, A Sternberg… - Frontiers in Sustainable …, 2019 - frontiersin.org
The global demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has minimal impact on the environment will require …

Embryo-mediated genome editing for accelerated genetic improvement of livestock

Z McLean, B Oback, G Laible - 2021 - agresearch.figshare.com
Selecting beneficial DNA variants is the main goal of animal breeding. However, this
process is inherently inefficient because each animal only carries a fraction of all desirable …

25th ANNIVERSARY OF CLONING BY SOMATIC-CELL NUCLEAR TRANSFER: Current applications of SCNT in advanced breeding and genome editing in livestock

C Galli, G Lazzari - Reproduction, 2021 - rep.bioscientifica.com
SCNT (somatic cell nuclear transfer) has complemented the toolbox of ARTs offering yet
another technique to reproduce animals in an unprecedented way. Despite remarkable …