Iron: an essential micronutrient for the legume-rhizobium symbiosis

EM Brear, DA Day, PMC Smith - Frontiers in plant science, 2013 - frontiersin.org
Legumes, which develop a symbiosis with nitrogen-fixing bacteria, have an increased
demand for iron. Iron is required for the synthesis of iron-containing proteins in the host …

[HTML][HTML] Transmembrane signaling across the ligand-gated FhuA receptor: crystal structures of free and ferrichrome-bound states reveal allosteric changes

KP Locher, B Rees, R Koebnik, A Mitschler, L Moulinier… - Cell, 1998 - cell.com
FhuA protein facilitates ligand-gated transport of ferrichrome-bound iron across Escherichia
coli outer membranes. X-ray analysis at 2.7 Å resolution reveals two distinct conformations …

The dhb operon of bacillus subtilisEncodes the biosynthetic template for the catecholic siderophore 2, 3-dihydroxybenzoate-glycine-threonine trimeric ester …

JJ May, TM Wendrich, MA Marahiel - Journal of Biological Chemistry, 2001 - ASBMB
Bacillus subtilis was reported to produce the catecholic siderophore itoic acid (2, 3-
dihydroxybenzoate (DHB)-glycine) in response to iron deprivation. However, by inspecting …

Mechanisms and regulation of reduction-based iron uptake in plants

W Schmidt - The New Phytologist, 1999 - cambridge.org
Despite the usually high abundance of iron (Fe) in soils, the low solubility of Fe-bearing
minerals restricts the available Fe pools in most aerobic soils to levels that are far below …

Molecular biology of cation transport in plants

TC Fox, ML Guerinot - Annual review of plant biology, 1998 - annualreviews.org
▪ Abstract This review summarizes current knowledge about genes whose products function
in the transport of various cationic macronutrients (K, Ca) and micronutrients (Cu, Fe, Mn …

Siderophore–drug complexes: potential medicinal applications of the 'Trojan horse'strategy

A Górska, A Sloderbach, MP Marszałł - Trends in pharmacological …, 2014 - cell.com
The ability of bacteria to develop resistance to antimicrobial agents poses problems in the
treatment of numerous bacterial infections. One method to circumvent permeability-mediated …

Siderophores as drug delivery agents: application of the “Trojan Horse” strategy

U Möllmann, L Heinisch, A Bauernfeind, T Köhler… - Biometals, 2009 - Springer
The outer membrane permeability barrier is an important resistance factor of bacterial
pathogens. In combination with drug inactivating enzymes, target alteration and efflux, it can …

A novel family of ubiquitous heavy metal ion transport proteins

IT Paulsen, MH Saier, Jr - The Journal of membrane biology, 1997 - Springer
We describe a novel diverse family of metal ion transporter (CDF) proteins (the cation
diffusion facilitator (CDF) family) with members occurring in both prokaryotes and …

FRD3, a member of the multidrug and toxin efflux family, controls iron deficiency responses in Arabidopsis

EE Rogers, ML Guerinot - The Plant Cell, 2002 - academic.oup.com
We present the cloning and characterization of an Arabidopsis gene, FRD3, involved in iron
homeostasis. Plants carrying any of the three alleles of frd3 constitutively express three …

Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport

IA Ehrnstorfer, ER Geertsma, E Pardon… - Nature Structural & …, 2014 - nature.com
Members of the SLC11 (NRAMP) family transport iron and other transition-metal ions across
cellular membranes. These membrane proteins are present in all kingdoms of life with a …