Disease Progression and Sphingolipids and Neurofilament Light Chain in Early Idiopathic Parkinson's Disease
Parkinson's disease (PD) lacks a biomarker for disease progression. To analyze how
cerebrospinal fluid (CSF), glucosylceramide (GlcCer), sphingomyelin (SM), or serum …
cerebrospinal fluid (CSF), glucosylceramide (GlcCer), sphingomyelin (SM), or serum …
Urinary bis (monacylglycerol) phosphate (BMP) levels are higher in LRRK2 and GBA1 variant carriers but do not predict disease progression in PPMI cohorts
K Merchant, T Simuni, J Fedler, C Caspell-Garcia… - 2022 - researchsquare.com
We quantified concentrations of three isoforms of the endolysosomal lipid, bis
(monoacylglycerol) phosphate (BMP) in urine of deeply phenotyped cohorts in the …
(monoacylglycerol) phosphate (BMP) in urine of deeply phenotyped cohorts in the …
[PDF][PDF] 酸性鞘磷脂酶与帕金森病
吴映， 陈煜森， 魏庄盛 - 新医学, 2020 - xinyixue.cn
酸性鞘磷脂酶(ASMase) 不仅介导溶酶体代谢, 参与膜结构的调节和信号转导,
而且对鞘磷脂转化为神经酰胺起关键作用. ASMase 由鞘磷脂磷酸二酯酶1 (SMPD1) 基因编码 …
而且对鞘磷脂转化为神经酰胺起关键作用. ASMase 由鞘磷脂磷酸二酯酶1 (SMPD1) 基因编码 …
[HTML][HTML] Manifestaciones cardiovasculares de la enfermedad de Parkinson: revisión de la literatura
N Henao Piedrahita, S Pérez Correa… - Acta Neurológica …, 2021 - scielo.org.co
La enfermedad de Parkinson es la segunda enfermedad neurodegenerativa más
prevalente en el mundo, y sus manifestaciones cardinales son la bradicinesia, el temblor y …
prevalente en el mundo, y sus manifestaciones cardinales son la bradicinesia, el temblor y …
Die Rolle der neutralen Sphingomyelinase bei der hippocampalen Neurogenese in der männlichen Maus
S Mbu Taku - 2023 - opus4.kobv.de
Background Alcohol consumption contributes to significant health deterioration, disability,
serious illness and even the death of up to 3 million people worldwide each year. Various …
serious illness and even the death of up to 3 million people worldwide each year. Various …
[PDF][PDF] Computational prediction and interpretation of the molecular effect and disease phenotype of missense variants in the human exome
W VRANKEN - 2022 - researchportal.vub.be
Despite the advent of new high-throughput experimental methods and the incredible amount
of data they produce, it remains challenging to understand the link between inherited …
of data they produce, it remains challenging to understand the link between inherited …
Misregulation of Mitochondria-Lysosome Contact Sites in GBA-linked Parkinson's Disease
S Kim - 2021 - search.proquest.com
Mitochondria-lysosome contacts are recently identified sites for mediating crosstalk between
both organelles, but their role in normal and diseased human neurons remains unknown …
both organelles, but their role in normal and diseased human neurons remains unknown …
Evolução dos sintomas não motores da doença de Parkinson em uma coorte de pacientes com doença de Gaucher tipo 1
MVMB Wilke - 2022 - lume.ufrgs.br
CONTEXTO: A doença de Gaucher (DG) é um erro inato do metabolismo causado pela
atividade deficiente da enzima beta-glucocerebrosidase (GCase), que catalisa a conversão …
atividade deficiente da enzima beta-glucocerebrosidase (GCase), que catalisa a conversão …
Characterizing Galectin and Lysosomal Rupture's Role in Spreading Parkinson Disease Pathology
K Burbidge - 2021 - search.proquest.com
The misfolding and subsequent accumulation of alpha-synuclein (α-syn) is central to the
pathogenesis of Parkinson's disease (PD). Several lines of evidence suggest pathological α …
pathogenesis of Parkinson's disease (PD). Several lines of evidence suggest pathological α …
[PDF][PDF] EXTRACTION DES INFORMATIONS PHYSIOLOGIQUES DES IMAGES TEP EN UTILISANT L'APPRENTISSAGE AUTOMATIQUE
O GASSARA - savoirs.usherbrooke.ca
Les maladies neurodégénératives, telles que la maladie de Parkinson, la maladie de
Huntington et la maladie d'Alzheimer, font l'objet d'études approfondies dans le domaine …
Huntington et la maladie d'Alzheimer, font l'objet d'études approfondies dans le domaine …