Anticancer and anti-inflammatory properties of mangiferin: A review of its molecular mechanisms

S Mei, H Ma, X Chen - Food and Chemical Toxicology, 2021 - Elsevier
Chronic inflammation is crucial for the pathological process of tumors due to increasing the
infiltration of cytokines, growth factors, and chemokines to the tumor microenvironment …

Protective mechanism of edible food plants against alcoholic liver disease with special mention to polyphenolic compounds

L Zhao, A Mehmood, D Yuan, M Usman, MA Murtaza… - Nutrients, 2021 - mdpi.com
Alcoholic liver disease (ALD) is one type of liver disease, causing a global healthcare
problem and mortality. The liver undergoes tissue damage by chronic alcohol consumption …

Mangiferin Alleviates Mitochondrial ROS in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration via Suppression of NF‐κB Signaling …

H Yu, G Hou, J Cao, Y Yin, Y Zhao… - Oxidative Medicine and …, 2021 - Wiley Online Library
Intervertebral disc degeneration (IVDD), one of the most common clinical diseases
worldwide, causes disc herniation and sciatica. Recent studies have identified the …

A reactive oxygen/nitrogen species-eliminating natural product-based nanomedicine for prevention and treatment of inflammatory liver injury

Y Zheng, M Du, H Shi, W Liu, C Zhuang, H Chen… - Chemical Engineering …, 2023 - Elsevier
Reactive oxygen and nitrogen species (RONS) are key signaling molecules that play an
important role in the progression of inflammatory diseases. Although various antioxidants …

Mangiferin prevents hepatocyte epithelial‐mesenchymal transition in liver fibrosis via targeting HSP27‐mediated JAK2/STAT3 and TGF‐β1/Smad pathway

X Zhang, X Zhang, X Ge, M Liu - Phytotherapy Research, 2022 - Wiley Online Library
Hepatocytes has been confirmed to undergo EMT and can be converted into myofibroblasts
during hepatic fibrogenesis. However, the mechanism of hepatocyte EMT regulation in …

Luteolin cooperated with metformin hydrochloride alleviates lipid metabolism disorders and optimizes intestinal flora compositions of high-fat diet mice

X Ge, H Chen, T Liu, L Chen, Y Huang, F Zeng, B Liu - Food & function, 2020 - pubs.rsc.org
Luteolin (LU) is a flavonoid compound and metformin hydrochloride (MH) is a kind of drug.
Studies have shown that both LU and MH have the function of hypoglycemic effect …

Non-targeted metabolomics reveals a modulatory effect of dha-enriched phosphatidylserine in high fat-diet induced non-alcoholic fatty liver disease in mice

H Zhang, S Tian, Q Zhao, Y Xu, L Bi, S Jiang… - Process Biochemistry, 2023 - Elsevier
To investigate the regulatory mechanism of docosahexaenoic acid-enriched
phosphatidylserine (DHA-PS) on high-fat diet (HFD)-induced non-alcoholic fatty liver …

Compound chenpi tea consumption reduces obesity‐related metabolic disorders by modulating gut microbiota and serum metabolites in mice

J Wang, J Hao, D Miao, P Xiao… - Journal of the Science …, 2024 - Wiley Online Library
BACKGROUND Compound chenpi tea (CCT) is a popular herbal beverage made from citri
reticulatae pericarpium, Ganoderma lucidum, and pu‐erh tea. This study aimed to …

The multifaceted role of mangiferin in health and diseases: A review

A Jangra, MK Arora, A Kisku, S Sharma - Advances in Traditional …, 2021 - Springer
A wide range of natural products including, flavonoids have been studied for their
therapeutic potential in different diseases. Mangiferin (2-cbd-glucopyranosyl 1, 3, 6, 7 …

Vine Tea (Ampelopsis grossedentata) Extract Attenuates CCl4‐Induced Liver Injury by Restoring Gut Microbiota Dysbiosis in Mice

Y Li, H Hu, H Yang, A Lin, H Xia… - Molecular Nutrition & …, 2022 - Wiley Online Library
Scope Vine tea (Ampelopsis grossedentata), a traditional Chinese tea, has displayed
various biological activities. The authors aim to investigate the effect of Vine Tea …