Regucalcin Is a Potential Regulator in Human Cancer: Aiming to Expand into Cancer Therapy

M Yamaguchi - Cancers, 2023 - mdpi.com
Simple Summary Regucalcin plays a multifunctional role in the regulation of cell function
and expresses a repressive effect in the growth of normal cells. Of note, there is increasing …

The relevance of acid sphingomyelinase as a potential target for therapeutic intervention in hepatic disorders: Current scenario and anticipated trends

IH Mir, C Thirunavukkarasu - Archives of Toxicology, 2023 - Springer
Acid sphingomyelinase (ASMase) serves as one of the most remarkable enzymes in
sphingolipid biology. ASMase facilitates the hydrolysis of sphingomyelin, yielding ceramide …

[HTML][HTML] Biomimetic formation of silver oxide nanoparticles through Diospyros montana bark extract: Its application in dye degradation, antibacterial and anticancer …

V Sujatha, G Kaviyasri, A Venkatesan… - Journal of King Saud …, 2023 - Elsevier
Objectives Remarkable potential of silver nanoparticles (NPs) makes its use efficient in both
biological as well as industrial applications. Post harvested NPs, free from other hazards …

The prominence of potential biomarkers in the diagnosis and management of hepatocellular carcinoma: current scenario and future anticipation

IH Mir, KC Jyothi… - Journal of Cellular …, 2022 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most aggressive and truculent types of
cancer. Early detection of HCC is a massive concern that can boost the overall survival rates …

Elucidation of 7, 8-dihydroxy flavone in complexing with the oxidative stress-inducing enzymes, its impact on radical quenching and DNA damage: an in silico and in …

IH Mir, AS Anilkumar, S Guha, AK Mohanty… - Journal of …, 2024 - Taylor & Francis
Oxidative stress (OS) has been attributed to the progression of various disorders, including
cancer, diabetes, and cardiovascular diseases. Several antioxidant compounds and free …

Predictive mutation signature of immunotherapy benefits in NSCLC based on machine learning algorithms

Z Liu, G Lin, Z Yan, L Li, X Wu, J Shi, J He… - Frontiers in …, 2022 - frontiersin.org
Background Developing prediction tools for immunotherapy approaches is a clinically
important and rapidly emerging field. The routinely used prediction biomarker is inaccurate …

[HTML][HTML] Pharmacologically inducing anoikis offers novel therapeutic opportunities in hepatocellular carcinoma

Y Wang, JS Fleishman, J Wang, J Chen, L Zhao… - Biomedicine & …, 2024 - Elsevier
Tumor metastasis occurs in hepatocellular carcinoma (HCC), leading to tumor progression
and therapeutic failure. Anoikis is a matrix detachment-induced apoptosis, also known as …

Stemness analysis in hepatocellular carcinoma identifies an extracellular matrix gene–related signature associated with prognosis and therapy response

L Chen, D Zhang, S Zheng, X Li, P Gao - Frontiers in Genetics, 2022 - frontiersin.org
Background: Tumor stemness is the stem-like phenotype of cancer cells, as a hallmark for
multiple processes in the development of hepatocellular carcinoma (HCC). However …

[HTML][HTML] Hepatocytic Ballooning in Non-alcoholic Steatohepatitis: Bridging the Knowledge Gap and Charting Future Avenues

T Singla, KN Muneshwar, AG Pathade, S Yelne - Cureus, 2023 - ncbi.nlm.nih.gov
Non-alcoholic steatohepatitis (NASH) is emerging as a significant global health concern,
characterized by hepatic lipid accumulation, inflammation, and hepatocellular injury …

Deciphering the calf thymus DNA binding potential of 5FU conjugated copper oxide nanoparticles along with its antiproliferative effects on liver cancer cells: A …

J Behera, IH Mir, KT Shyam, S Guha, V Sujatha… - Journal of Molecular …, 2023 - Elsevier
The current study accomplished 5-fluorouracil conjugated copper oxide nanoparticles
(5FUcCuONPs) and assessed their DNA binding and antiproliferative capabilities using an …