Acute respiratory distress syndrome (ARDS) is difficult to treat and is associated with a high
mortality rate. The most severe form of coronavirus disease 2019 (COVID-19) also leads to …

This review describes targeting neutrophils as a potential therapeutic strategy for acute
respiratory distress syndrome (ARDS) associated with coronavirus disease 2019 (COVID …

Neutrophilic inflammatory diseases, such as chronic obstructive pulmonary disease (COPD),
acute respiratory distress syndrome (ARDS), or psoriasis, exert a huge burden on the global …

Acute lung injury (ALI) is an acute, progressive hypoxic respiratory failure that could develop
into acute respiratory distress syndrome (ARDS) with very high mortality rate. ALI is believed …

Aims Infiltration of activated neutrophils into the lungs is a hallmark of acute respiratory
distress syndrome (ARDS). Neutrophilic inflammation, particularly neutrophil extracellular …

Microglial activation-induced neuroinflammation contributes to onset and progression of
sporadic and hereditary Parkinson's disease (PD). Activated microglia secrete pro …

Neutrophil infiltration plays a significant pathological role in inflammatory diseases. NADPH
oxidase type 2 (NOX2) is a respiratory burst oxidase that generates large amounts of …

Background and Purpose Acute respiratory distress syndrome (ARDS) is a catastrophic
pulmonary inflammatory dysfunction with a high mortality rate. An overwhelming immune …

Background Acute lung injury (ALI) is a severe life-threatening inflammatory disease.
Neutrophil activation is a major pathogenic factor in ALI. Protein kinase B (PKB)/AKT …

GPR84 is a proinflammatory G protein-coupled receptor that mediates myeloid immune cell
functions. Blocking GPR84 with antagonists is a promising approach for treating …