Simple Summary Improving the response, quality of life and survival of oncologic patients
through the design and application of the most appropriate treatment for each case is a great …

The substance P (SP)/neurokinin-1 receptor (NK-1R) system is involved in cancer
progression. NK-1R, activated by SP, promotes tumor cell proliferation and migration …

New, promising molecular targets to block tumor development and new compounds capable
of specifically destroying cancer cells must be urgently investigated. In recent years, the …

Peptides mediate cancer progression favoring the mitogenesis, migration, and invasion of
tumor cells, promoting metastasis and anti-apoptotic mechanisms, and facilitating …

The important role played by the substance P (SP)/neurokinin-1 receptor (NK-1R) system in
cancer is reviewed: this includes tumor cell proliferation and migration, anti-apoptotic …

Definition Peptidergic systems show promise as targets for fighting tumors. While some
peptides encourage the growth and spread of tumor cells and angiogenic mechanisms …

As things stand in 2023, metastatic osteosarcoma commonly results in death. There has
been little treatment progress in recent decades. To redress the poor prognosis of metastatic …

Recently, the substance P (SP)/neurokinin-1 receptor (NK-1R) system has been found to be
involved in various human pathophysiological disorders including the symptoms of …

Drug repositioning (DR) is the process of finding new clinical indications for existing drugs
(Nosengo, 2016; Corsello et al., 2017). In the current “target rich-lead poor” scenario of drug …

目前研究已经发现神经肽(SP)/神经激肽1 受体(NK-1R) 拮抗剂系统参与了包括2019
冠状病毒病(COVID-19) 症状在内的多种人体生理疾病. 肿瘤学领域的最新研究表明: NK-1R …