Periodontitis is a prevalent chronic disease that results in loss of periodontal ligament and
bone resorption. Triggered by pathogens and prolonged inflammation, periodontitis is …

An unusual form of lung disease has begun to affect some children with systemic juvenile
idiopathic arthritis (JIA), coincident with increasing utilization of interleukin‐1 (IL‐1) and IL‐6 …

Pseudo-progression and flare-up phenomena constitute a novel diagnostic challenge in the
follow-up of patients treated with immune-oncology drugs. We present a case study on …

At the turn of the century, researchers discovered a unique subtype of T helper cells that
secretes IL-17 and defined it as Th17. The latest study found that Th17 cells play both …

The non-pathogenic TH17 subset of helper T cells clears fungal infections, whereas
pathogenic TH17 cells cause inflammation and tissue damage; however, the mechanisms …

Autoimmune diseases are a diverse set of conditions defined by organ damage due to
abnormal innate and acquired immune system responses. The pathophysiology of …

Cold atmospheric plasma (CAP) has been studied and clinically applied to treat chronic
wounds, cancer, periodontitis, and other diseases. CAP exerts cytotoxic, bactericidal, cell …

Selective inhibitors targeting the first bromodomain (BD1) or the second bromodomain
(BD2) of the bromodomain and extra terminal domain (BET) proteins have triggered …

The immune response to an allograft activates lymphocytes with the capacity to cause
rejection. Activation of CD4+ CD25+ Foxp3+ T regulatory cells (Treg) can down-regulate …

Background Oral lichen planus (OLP) is a T cell-mediated chronic autoimmune disease,
whose pathogenesis and etiology are not entirely understood. OLP is characterized by …