Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …

Angiogenesis, the growth of new blood vessels, is essential in the pathogenesis of joint
inflammatory disorders such as rheumatoid arthritis (RA) and osteoarthritis (OA), facilitating …

The immunomodulatory potential of mesenchymal stromal cells (MSCs) and regulatory T
cells (T-reg) is well recognized by translational scientists in the field of regenerative …

Rheumatoid arthritis (RA) is the most common immune-mediated inflammatory disease
characterized by chronic synovitis that hardly resolves spontaneously. The current treatment …

Type 1 diabetes mellitus (T1DM) is one of the autoimmune diseases characterized by beta-
cell dysfunction with serious health complications. Br-MSCs represent a novel valid …

Background This study aims to evaluate the quality of preclinical data, determine the effect
sizes, and identify experimental measures that inform efficacy using mesenchymal stromal …

Abstract Background Mesenchymal stem cells (MSCs) exhibit active abilities to suppress or
modulate deleterious immune responses by various molecular mechanisms. These cells are …

Rheumatoid arthritis (RA) is a disease of the joints that causes decreased quality of life.
Mesenchymal stromal cells (MSCs) have immunosuppressive properties, with possible use …

Cells can communicate with each other through extracellular vesicles (EVs), which are
membrane-bound structures that transport proteins, lipids and nucleic acids. These …

Rheumatoid arthritis (RA) is considered to be a degenerative and progressive autoimmune
disorder. Although several medicinal regimens are used to treat RA, potential adverse …