Advancing biomaterials of human origin for tissue engineering

FM Chen, X Liu - Progress in polymer science, 2016 - Elsevier
Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

Extracellular matrix-derived biomaterials in engineering cell function

H Xing, H Lee, L Luo, TR Kyriakides - Biotechnology advances, 2020 - Elsevier
Extracellular matrix (ECM) derived components are emerging sources for the engineering of
biomaterials that are capable of inducing desirable cell-specific responses. This review …

Investigating human disease using stem cell models

JL Sterneckert, P Reinhardt, HR Schöler - Nature Reviews Genetics, 2014 - nature.com
Tractable and accurate disease models are essential for understanding disease
pathogenesis and for developing new therapeutics. As stem cells are capable of self …

Functional extracellular matrix hydrogel modified with MSC‐derived small extracellular vesicles for chronic wound healing

S Ma, H Hu, J Wu, X Li, X Ma, Z Zhao, Z Liu… - Cell …, 2022 - Wiley Online Library
Objectives Diabetic wound healing remains a global challenge in the clinic and in research.
However, the current medical dressings are difficult to meet the demands. The primary goal …

Engineered delivery strategies for enhanced control of growth factor activities in wound healing

Y Niu, Q Li, Y Ding, L Dong, C Wang - Advanced drug delivery reviews, 2019 - Elsevier
Growth factors (GFs) are versatile signalling molecules that orchestrate the dynamic, multi-
stage process of wound healing. Delivery of exogenous GFs to the wound milieu to mediate …

Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues

GM Cunniffe, PJ Díaz-Payno, EJ Sheehy, SE Critchley… - Biomaterials, 2019 - Elsevier
Biological scaffolds generated from tissue-derived extracellular matrix (ECM) are commonly
used clinically for soft tissue regeneration. Such biomaterials can enhance tissue-specific …

[HTML][HTML] An adhesive gelatin-coated small intestinal submucosa composite hydrogel dressing aids wound healing

L Wang, F Liu, X Zhai, W Dong, W Wei, Z Hu - International Journal of …, 2023 - Elsevier
It is a challenging clinical task to determine how to repair large-area skin defects better.
Traditional wound dressings (eg, cotton and gauze) can only be used as a dressing; …

[HTML][HTML] Human microphysiological models of intestinal tissue and gut microbiome

SN Steinway, J Saleh, BK Koo, D Delacour… - … in bioengineering and …, 2020 - frontiersin.org
The gastrointestinal (GI) tract is a complex system responsible for nutrient absorption,
digestion, secretion, and elimination of waste products that also hosts immune surveillance …

[HTML][HTML] Membranous extracellular matrix-based scaffolds for skin wound healing

LC Da, YZ Huang, HQ Xie, BH Zheng, YC Huang… - Pharmaceutics, 2021 - mdpi.com
Membranous extracellular matrix (ECM)-based scaffolds are one of the most promising
biomaterials for skin wound healing, some of which, such as acellular dermal matrix, small …

Small intestinal submucosa: superiority, limitations and solutions, and its potential to address bottlenecks in tissue repair

G Cao, Y Huang, K Li, Y Fan, H Xie, X Li - Journal of materials …, 2019 - pubs.rsc.org
Over the past few decades, small intestinal submucosa (SIS), a naturally occurring
decellularized extracellular matrix (ECM), has attracted much attention in tissue repair …