American Association of Clinical Endocrinology clinical practice guideline for the diagnosis and management of nonalcoholic fatty liver disease in primary care and …

K Cusi, S Isaacs, D Barb, R Basu, S Caprio… - Endocrine Practice, 2022 - Elsevier
Objective To provide evidence-based recommendations regarding the diagnosis and
management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis …

The complex link between NAFLD and type 2 diabetes mellitus—mechanisms and treatments

G Targher, KE Corey, CD Byrne… - … reviews Gastroenterology & …, 2021 - nature.com
Nonalcoholic fatty liver disease (NAFLD) has reached epidemic proportions worldwide.
NAFLD and type 2 diabetes mellitus (T2DM) are known to frequently coexist and act …

AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease

ME Rinella, BA Neuschwander-Tetri, MS Siddiqui… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …

Non-alcoholic fatty liver disease and risk of fatal and non-fatal cardiovascular events: an updated systematic review and meta-analysis

A Mantovani, A Csermely, G Petracca… - The lancet …, 2021 - thelancet.com
Background Studies have reported a significant association between non-alcoholic fatty liver
disease (NAFLD) and increased incidence of cardiovascular disease (CVD). However, the …

Association of type 2 diabetes with cancer: a meta-analysis with bias analysis for unmeasured confounding in 151 cohorts comprising 32 million people

S Ling, K Brown, JK Miksza, L Howells… - Diabetes …, 2020 - Am Diabetes Assoc
BACKGROUND AND PURPOSE Whether the association between type 2 diabetes (T2D)
and cancer is causal remains controversial. The goal of this work is to assess the robustness …

[HTML][HTML] Hepatokines and metabolism: Deciphering communication from the liver

SO Jensen-Cody, MJ Potthoff - Molecular metabolism, 2021 - Elsevier
Background The liver is a key regulator of systemic energy homeostasis and can sense and
respond to nutrient excess and deficiency through crosstalk with multiple tissues. Regulation …

Comparative burden of metabolic dysfunction in lean NAFLD vs non-lean NAFLD-a systematic review and meta-analysis

A Tang, CH Ng, PH Phang, KE Chan, YH Chin… - Clinical …, 2023 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD) is traditionally associated with
obesity. However, there is a subtype of NAFLD, namely NAFLD in lean, that occurs without …

[HTML][HTML] Nutraceutical approaches to non-alcoholic fatty liver disease (NAFLD): A position paper from the International Lipid Expert Panel (ILEP)

M Rizzo, A Colletti, PE Penson, N Katsiki… - Pharmacological …, 2023 - Elsevier
Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) is a common condition affecting around
10–25% of the general adult population, 15% of children, and even> 50% of individuals who …

[HTML][HTML] Metabolic dysfunction-associated fatty liver disease and cardiovascular disease: a meta-analysis

W Wen, H Li, C Wang, C Chen, J Tang… - Frontiers in …, 2022 - frontiersin.org
Background Metabolic dysfunction-associated fatty liver disease [MAFLD, formerly known as
nonalcoholic fatty liver disease (NAFLD)] is one of the most important causes of liver disease …

Diabetes and cirrhosis: current concepts on diagnosis and management

L Castera, K Cusi - Hepatology, 2023 - journals.lww.com
Type 2 diabetes mellitus is often associated with cirrhosis as comorbidities, acute illness,
medications, and other conditions profoundly alter glucose metabolism. Both conditions are …