PGC‐1α, Inflammation, and Oxidative Stress: An Integrative View in Metabolism

S Rius-Pérez, I Torres-Cuevas, I Millán… - Oxidative medicine …, 2020 - Wiley Online Library
Peroxisome proliferator‐activated receptor‐γ coactivator (PGC)‐1α is a transcriptional
coactivator described as a master regulator of mitochondrial biogenesis and function …

[HTML][HTML] Role of phytochemicals in cancer chemoprevention: Insights

BP George, R Chandran, H Abrahamse - Antioxidants, 2021 - mdpi.com
Cancer is a condition where the body cells multiply in an uncontrollable manner.
Chemoprevention of cancer is a broad term that describes the involvement of external …

Potential adverse effects of resveratrol: A literature review

A Shaito, AM Posadino, N Younes, H Hasan… - International journal of …, 2020 - mdpi.com
Due to its health benefits, resveratrol (RE) is one of the most researched natural
polyphenols. Resveratrol's health benefits were first highlighted in the early 1990s in the …

[HTML][HTML] The role of polyphenols in human health and food systems: A mini-review

H Cory, S Passarelli, J Szeto, M Tamez, J Mattei - Frontiers in nutrition, 2018 - frontiersin.org
This narrative mini-review summarizes current knowledge of the role of polyphenols in
health outcomes–and non-communicable diseases specifically–and discusses the …

[HTML][HTML] The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy

C Grinán-Ferré, A Bellver-Sanchis, V Izquierdo… - Ageing Research …, 2021 - Elsevier
While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …

Caloric restriction mimetics against age-associated disease: targets, mechanisms, and therapeutic potential

F Madeo, D Carmona-Gutierrez, SJ Hofer, G Kroemer - Cell metabolism, 2019 - cell.com
The increase in life expectancy has boosted the incidence of age-related pathologies
beyond social and economic sustainability. Consequently, there is an urgent need for …

Health benefits of resveratrol: Evidence from clinical studies

AP Singh, R Singh, SS Verma, V Rai… - Medicinal research …, 2019 - Wiley Online Library
Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases

AE Kane, DA Sinclair - Circulation research, 2018 - Am Heart Assoc
The sirtuin family of nicotinamide adenine dinucleotide–dependent deacylases (SIRT1–7)
are thought to be responsible, in large part, for the cardiometabolic benefits of lean diets and …

[HTML][HTML] Antibacterial and antifungal properties of resveratrol

M Vestergaard, H Ingmer - International Journal of Antimicrobial Agents, 2019 - Elsevier
Resveratrol is a naturally occurring polyphenolic antioxidant that has received massive
attention for its potential health benefits, including anticarcinogenesis, anti-aging and …

Surface coating of zein nanoparticles to improve the application of bioactive compounds: A review

Y Yuan, M Ma, Y Xu, D Wang - Trends in Food Science & Technology, 2022 - Elsevier
Background As an excellent delivery material for bioactive compounds, zein nanoparticles
are limited by colloidal instability. Recently, the development of their surface coating has …