Naringenin and hesperidin as promising alternatives for prevention and co-adjuvant therapy for breast cancer

MB Madureira, VM Concato, EMS Cruz… - Antioxidants, 2023 - mdpi.com
Citrus (genus Citrus L.) fruits are essential sources of bioactive compounds with antioxidant
properties, such as flavonoids. These polyphenolic compounds are divided into subclasses …

Ginsenosides: changing the basic hallmarks of cancer cells to achieve the purpose of treating breast cancer

R Jiang, Z Fang, H Zhang, J Xu, J Zhu, K Chen… - Chinese Medicine, 2023 - Springer
In 2021, breast cancer accounted for a substantial proportion of cancer cases and
represented the second leading cause of cancer deaths among women worldwide. Although …

Cannabinoids and standardized cannabis extracts inhibit migration, invasion, and induce apoptosis in MCF-7 cells through FAK/MAPK/Akt/NF-κB signaling

W Suttithumsatid, W Sukketsiri… - Toxicology in Vitro, 2023 - Elsevier
Background Breast cancer is the highest incidence of all types of cancer in women, and the
cancer metastasis process accounts for a majority of cancer deaths. Two major …

The role of peptides in reversing chemoresistance of breast cancer: current facts and future prospects

Y Huang, H Peng, A Zeng, L Song - Frontiers in Pharmacology, 2023 - frontiersin.org
Breast cancer is the first malignant tumor in women, and its incidence is also increasing year
by year. Chemotherapy is one of the standard therapies for breast cancer, but the resistance …

Escherichia coli infection mediates pyroptosis via activating p53-p21 pathway-regulated apoptosis and cell cycle arrest in bovine mammary epithelial cells

C Zhuang, J Zhao, S Zhang, M Shahid - Microbial pathogenesis, 2023 - Elsevier
Escherichia coli (E. coli) is a major environmental pathogen that causes mammary tissue
damage and cell death, which results in substantial economic losses. Pyroptosis, a novel …

Mechanism of ferroptosis in breast cancer and research progress of natural compounds regulating ferroptosis

A Ge, Q He, D Zhao, Y Li, J Chen… - Journal of Cellular …, 2024 - Wiley Online Library
Breast cancer is the most prevalent cancer worldwide and its incidence increases with age,
posing a significant threat to women's health globally. Due to the clinical heterogeneity of …

5, 6-Dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) induces apoptosis in breast cancer cells through inhibiting of Mcl-1 expression

YH Kuo, TC Lai, CH Chang, HC Hsieh, FM Yang… - Scientific Reports, 2023 - nature.com
The effective treatment of breast cancer remains a profound clinical challenge, especially
due to drug resistance and metastasis which unfortunately arise in many patients. The …

Investigating the Function of Human Jumping Translocation Breakpoint Protein (hJTB) and Its Interacting Partners through In-Solution Proteomics of MCF7 Cells

M Jayathirtha, D Whitham, S Alwine, M Donnelly… - Molecules, 2022 - mdpi.com
Human jumping translocation breakpoint (hJTB) gene is located on chromosome 1q21 and
is involved in unbalanced translocation in many types of cancer. JTB protein is ubiquitously …

Apigenin promotes apoptosis of 4T1 cells through PI3K/AKT/Nrf2 pathway and improves tumor immune microenvironment in vivo

C Zhang, Y Liao, T Li, H Zhong, L Shan… - Toxicology …, 2024 - academic.oup.com
Abstract The 2022 US Cancer Statistics show that breast cancer is one of the most common
cancers in women. Epidemiology has shown that adding flavonoids to the diet inhibits …

[HTML][HTML] Targeting cancer metabolic vulnerabilities for advanced therapeutic efficacy

TA Muluh, X Shu, Y Ying - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cancer metabolism is how cancer cells utilize nutrients and energy to support their growth
and proliferation. Unlike normal cells, cancer cells have a unique metabolic profile that …