[HTML][HTML] A review of the global epidemiology of scrub typhus

G Xu, DH Walker, D Jupiter, PC Melby… - PLoS neglected tropical …, 2017 - journals.plos.org
Scrub typhus is a serious public health problem in the Asia-Pacific area. It threatens one
billion people globally, and causes illness in one million people each year. Caused by …

[HTML][HTML] Diagnosis of scrub typhus: recent advancements and challenges

D Kala, S Gupta, R Nagraik, V Verma, A Thakur… - 3 Biotech, 2020 - Springer
Scrub typhus is a mite-borne, acute febrile illness caused by the bacterium Orientia
tsutsugamushi. It is a re-emerging infectious disease of the tsutsugamushi triangle. Scrub …

[HTML][HTML] Orientia tsutsugamushi: the dangerous yet neglected foe from the East

A Banerjee, S Kulkarni - International Journal of Medical Microbiology, 2021 - Elsevier
Orientia tsutsugamushi (OT), the causative agent of the vector-borne Scrub typhus zoonotic
disease in humans, is a unique microorganism that exists in the Asia-Pacific region since a …

[HTML][HTML] Diversification of Orientia tsutsugamushi genotypes by intragenic recombination and their potential expansion in endemic areas

G Kim, NY Ha, CK Min, HI Kim, NTH Yen… - PLoS neglected …, 2017 - journals.plos.org
Background Scrub typhus is a mite-borne febrile disease caused by O. tsutsugamushi
infection. Recently, emergence of scrub typhus has attracted considerable attention in …

[HTML][HTML] Orientia tsutsugamushi: A neglected but fascinating obligate intracellular bacterial pathogen

J Salje - PLoS pathogens, 2017 - journals.plos.org
Our understanding of the molecular systems that bacteria have developed over millennia of
evolutionary tinkering remains limited compared with the incredible diversity of the bacterial …

[HTML][HTML] Orientia tsutsugamushi Stimulates an Original Gene Expression Program in Monocytes: Relationship with Gene Expression in Patients with Scrub Typhus

W Tantibhedhyangkul, T Prachason… - PLoS neglected …, 2011 - journals.plos.org
Orientia tsutsugamushi is the causal agent of scrub typhus, a public health problem in the
Asia-Pacific region and a life-threatening disease. O. tsutsugamushi is an obligate …

Evidence for a peptidoglycan‐like structure in Orientia tsutsugamushi

S Atwal, S Giengkam, S Chaemchuen… - Molecular …, 2017 - Wiley Online Library
Bacterial cell walls are composed of the large cross‐linked macromolecule peptidoglycan,
which maintains cell shape and is responsible for resisting osmotic stresses. This is a highly …

[HTML][HTML] Immunization with an Autotransporter Protein of Orientia tsutsugamushi Provides Protective Immunity against Scrub Typhus

NY Ha, P Sharma, G Kim, Y Kim, CK Min… - PLoS neglected …, 2015 - journals.plos.org
Background Scrub typhus is an acute febrile disease caused by Orientia tsutsugamushi
infection. Recently, the rapid increase of scrub typhus incidence in several countries within …

[HTML][HTML] Subversion of host cell signaling by Orientia tsutsugamushi

Y Ge, Y Rikihisa - Microbes and Infection, 2011 - Elsevier
Progress has been made in deciphering the mechanisms on Orientia tsutsugamushi-host
interaction. The genome sequencing, microarray and proteomic analyses of this ancient …

An Autotransporter Protein from Orientia tsutsugamushi Mediates Adherence to Nonphagocytic Host Cells

NY Ha, NH Cho, YS Kim, MS Choi… - Infection and immunity, 2011 - Am Soc Microbiol
Orientia tsutsugamushi, the causative agent of scrub typhus, is an obligate intracellular
pathogen whose mechanism of cellular adhesion and invasion is poorly characterized …